CAS No. 6100-74-9

Batch: Purity:99.94
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3'-Hydroxy-4'-methoxyacetophenone Chemical Structure
Chemical Structure
Check the 3'-Hydroxy-4'-methoxyacetophenone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6100-74-9
Molecular Formula

C9H10O3
Molecular Weight (MW) 166.17
SMILES CC(=O)C1=CC(=C(C=C1)OC)O

Ordering Information

Biological Activity

3'-Hydroxy-4'-methoxyacetophenone, also known as isoacetovanillone, is a natural phenolic compound and acetophenone derivative exhibiting potent anti-inflammatory and antioxidant properties. The compound targets cellular oxidative stress mechanisms by suppressing reactive oxygen species generation and regulating inflammatory signaling cascades, particularly the NF-kB pathway. Consequently, it downregulates proinflammatory cytokine expression and protects cells from oxidative damage and inflammatory responses.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 33 mg/mL (198.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 33 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.