CAS No. 7423-93-0
Batch:
Purity:98.72
Chemical Structure
Check the
3-Chloro-L-tyrosine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 7423-93-0 | |
|---|---|---|
| Molecular Formula |
C9H10ClNO3 |
|
| Molecular Weight (MW) | 215.63 | |
| SMILES | C1=CC(=C(C=C1CC(C(=O)O)N)Cl)O |
3-Chloro-L-tyrosine is a halogenated amino acid derivative that serves as a specific biomarker of myeloperoxidase-catalyzed protein oxidation and oxidative stress. Myeloperoxidase utilizes hydrogen peroxide and chloride ions to generate hypochlorous acid, leading to chlorination of tyrosine residues in proteins such as low-density lipoprotein. Accumulation of 3-chlorotyrosine reflects neutrophil activation and oxidative tissue damage during inflammation and vascular pathologies. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 9 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.