CAS No. 6249-56-5

Batch: Purity:99.83
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(3-Carboxypropyl)trimethylammonium chloride Chemical Structure
Chemical Structure
Check the (3-Carboxypropyl)trimethylammonium chloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6249-56-5
Molecular Formula

C7H16ClNO2
Molecular Weight (MW) 181.66
SMILES [Cl-].C[N+](C)(C)CCCC(O)=O

Ordering Information

Biological Activity

(3-Carboxypropyl)trimethylammonium chloride (γ-butyrobetaine) is a gut microbial metabolite derived from dietary L-carnitine. It acts as a key intermediate in carnitine biosynthesis and is further metabolized by intestinal microbiota into trimethylamine, which host hepatic enzymes convert to trimethylamine N-oxide (TMAO). This metabolic cascade downstream alters endothelial function and lipid metabolism, contributing to pro-atherogenic cardiovascular phenotypes. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 36 mg/mL (198.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 36 mg/mL
Ethanol 36 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.