CAS No. 500-99-2
Batch:
Purity:99
Chemical Structure
Check the
3,5-Dimethoxyphenol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 500-99-2 | |
|---|---|---|
| Molecular Formula |
C8H10O3 |
|
| Molecular Weight (MW) | 154.16 | |
| SMILES | COC1=CC(=CC(=C1)O)OC |
Biological Activity
3,5-Dimethoxyphenol is a phenolic derivative and toxin metabolite identified in humans following the ingestion of yew (Taxus baccata) leaves. As a plant-derived metabolite, it serves as a key chemical marker for yew exposure and intoxication. Studies indicate that phenolic metabolites from yew alter cellular oxidative stress levels and modulate metabolic pathways, impacting cell viability and cellular toxicity phenotypes. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
30 mg/mL
(194.6 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.