CAS No. 10210-17-0

Batch: Purity:99.81
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3-(4-Hydroxyphenyl)-1-propanol Chemical Structure
Chemical Structure
Check the 3-(4-Hydroxyphenyl)-1-propanol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 10210-17-0
Molecular Formula

C9H12O2
Molecular Weight (MW) 152.19
SMILES C1=CC(=CC=C1CCCO)O

Biological Activity

3-(4-Hydroxyphenyl)-1-propanol serves as a specialized chemical reagent and synthetic precursor used for the preparation of (−)-centrolobine, a natural diarylheptanoid compound possessing marked anti-leishmanial activity. Through this synthetic utility, the resulting centrolobine molecules target *Leishmania* protozoan parasites, impairing cellular survival pathways and inhibiting parasite proliferation and biological viability in infectious disease research models. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 30 mg/mL (197.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 30 mg/mL
Ethanol 30 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Croft SL, et al. Clin Microbiol Infect. 2011;17(10):1478-83.

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Note: Technical data last updated: Sep 1, 2026.