CAS No. 2316-26-9
Batch:
Purity:99.84
Chemical Structure
Check the
3,4-Dimethoxycinnamic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 3-(3,4-dimethoxyphenyl)prop-2-enoic acid | |
|---|---|---|
| CAS Number | 2316-26-9 | |
| Molecular Formula |
C11H12O4 |
|
| Molecular Weight (MW) | 208.21 | |
| SMILES | COC1=C(C=C(C=C1)C=CC(=O)O)OC | |
| InChIKey | HJBWJAPEBGSQPR-UHFFFAOYSA-N |
3,4-Dimethoxycinnamic acid is a bioavailable coffee-derived cinnamic acid derivative that functions as a small-molecule anti-prion compound targeting cellular prion protein (PrP). By potently binding to PrP, it interferes with the misfolding cascade and prevents the accumulation of pathogenic, misfolded prion protein aggregates. This inhibition of prion protein conversion suppresses associated neurotoxic pathways, providing a valuable chemical tool for investigating prion disease propagation and therapeutic interventions. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
42 mg/mL
(201.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 3,4-Dimethoxycinnamic acid Solubility in DMSO
- 3,4-Dimethoxycinnamic acid Stock Solution
- 3,4-Dimethoxycinnamic acid Storage
- 3,4-Dimethoxycinnamic acid Stability
- 3,4-Dimethoxycinnamic acid Molecular Weight
- 3,4-Dimethoxycinnamic acid SMILES
- 3,4-Dimethoxycinnamic acid Chemical Structure (2D and 3D)
- 3,4-Dimethoxycinnamic acid SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.