CAS No. 10516-71-9

Batch: Purity:99.46
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3-(3-Methoxyphenyl)propionic acid Chemical Structure
Chemical Structure
Check the 3-(3-Methoxyphenyl)propionic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 10516-71-9
Molecular Formula

C10H12O3
Molecular Weight (MW) 180.20
SMILES COC1=CC=CC(=C1)CCC(=O)O

Biological Activity

3-(3-Methoxyphenyl)propionic acid is a naturally occurring endogenous human metabolite and organic phenolic acid derivative excreted in urine. As a microbial degradation product of dietary flavonoids and polyphenols, it plays a role in gut microbiota-host metabolic crosstalk and cellular homeostasis. Biological studies indicate that this metabolite exhibits antioxidant properties, helping attenuate oxidative stress and modulate cellular metabolic pathways. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 36 mg/mL (199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Rechner AR, et al. Free Radic Biol Med. 2002;33(2):220-35.

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Note: Technical data last updated: Sep 1, 2026.