CAS No. 68236-13-5

(2S)-6-Prenylnaringenin Chemical Structure
Chemical Structure
Check the (2S)-6-Prenylnaringenin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 68236-13-5
Molecular Formula

C20H20O5

Molecular Weight (MW) 340.37
SMILES OC1=C2C(O[C@H](C3=CC=C(O)C=C3)CC2=O)=CC(O)=C1C/C=C(C)/C

Ordering Information

Biological Activity

(2S)-6-Prenylnaringenin is a naturally occurring prenylflavonoid compound that functions as a positive allosteric modulator of GABAA receptors, specifically targeting the α+β- binding interface. By potentiating GABA-mediated inhibitory neurotransmission within the central nervous system, this agent regulates neuronal excitability and downstream GABAergic signaling pathways. It demonstrates high functional efficacy in forebrain tissues, where enhanced receptor activation contributes to modulated synaptic inhibition and altered neural network dynamics. [1]

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Note: Technical data last updated: Sep 1, 2026.