CAS No. 14197-60-5

Batch: Purity:98.93
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20S-Ginsenoside Rg3 Chemical Structure
Chemical Structure
Check the 20S-Ginsenoside Rg3 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 14197-60-5
Molecular Formula

C42H72O13
Molecular Weight (MW) 785.01
SMILES CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)C)O)C)O)C

Ordering Information

Biological Activity

20S-Ginsenoside Rg3 is a natural triterpenoid saponin exhibiting anti-inflammatory, antioxidative, anti-angiogenic, and anticancer activities. It modulates cellular signaling pathways including NF-kB, AKT/mTOR, and VEGF, thereby inhibiting tumor cell proliferation, migration, and capillary tube formation while inducing apoptosis in cancer models. Additionally, it displays neuroprotective and cognition-enhancing effects by dampening neuroinflammation and oxidative stress.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (127.38 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 80 mg/mL
Water ˂1 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.