CAS No. 52286-74-5
Batch:
Purity:99.49
Chemical Structure
Check the
(20S)Ginsenoside Rg2
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 52286-74-5 | |
|---|---|---|
| Molecular Formula |
C42H72O13 |
|
| Molecular Weight (MW) | 785.01 | |
| SMILES | CC1C(C(C(C(O1)OC2C(C(C(OC2OC3CC4(C(CC(C5C4(CCC5C(C)(CCC=C(C)C)O)C)O)C6(C3C(C(CC6)O)(C)C)C)C)CO)O)O)O)O)O |
(20S)Ginsenoside Rg2 is a natural protopanaxatriol saponin derived from red ginseng that exhibits antiproliferative, anti-inflammatory, and neuroprotective activities. It modulates key cellular signaling cascades including the NF-kB, MAPK, and PI3K/AKT pathways, leading to down-regulation of pro-inflammatory cytokines and cell adhesion molecules. Furthermore, (20S)Ginsenoside Rg2 suppresses cancer cell proliferation and induces cell cycle arrest and apoptosis by regulating apoptotic pathway proteins. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(127.38 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.