CAS No. 64-04-0
Batch:
Purity:98
Chemical Structure
Check the
2-Phenylethylamine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 64-04-0 | |
|---|---|---|
| Molecular Formula |
C8H11N |
|
| Molecular Weight (MW) | 121.18 | |
| SMILES | C1=CC=C(C=C1)CCN |
2-Phenylethylamine is a natural monoamine alkaloid that acts as an endogenous agonist of trace amine-associated receptor 1 (TAAR1). Activation of TAAR1 and interaction with monoaminergic transporters inhibit neurotransmitter reuptake and stimulate the release of dopamine, norepinephrine, and serotonin in the central nervous system. These neurochemical actions modulate downstream monoaminergic signaling pathways to regulate neurological functions and behavioral phenotypes.
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(825.21 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | 12 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.