CAS No. 156-06-9

Batch: Purity:99.44
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2-Oxo-3-phenylpropanoic acid Chemical Structure
Chemical Structure
Check the 2-Oxo-3-phenylpropanoic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 156-06-9
Molecular Formula

C9H8O3
Molecular Weight (MW) 164.16
SMILES C1=CC=C(C=C1)CC(=O)C(=O)O

Biological Activity

2-Oxo-3-phenylpropanoic acid (phenylpyruvic acid) is an alpha-keto acid metabolite that serves as an enzymatic substrate for lactate dehydrogenase in the biochemical synthesis of 3-phenyllactic acid. Reduction of phenylpyruvic acid via lactate dehydrogenase modulates amino acid catabolic pathways and organic acid biosynthesis, facilitating downstream metabolic turnover and antimicrobial metabolite generation in biological systems.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 32 mg/mL (194.93 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.