CAS No. 653-63-4

Batch: Purity:99.77
Check CoA
2'-Deoxyadenosine 5'-monophosphate Chemical Structure
Chemical Structure
Check the 2'-Deoxyadenosine 5'-monophosphate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 653-63-4
Molecular Formula

C10H14N5O6P
Molecular Weight (MW) 331.22
SMILES NC1=C2N=C[N](C3CC(O)C(CO[P](O)(O)=O)O3)C2=NC=N1

Biological Activity

2'-Deoxyadenosine 5'-monophosphate (5'-dAMP) is an endogenous purine deoxyribonucleotide metabolite involved in cellular nucleic acid synthesis and purine salvage pathways. As a central metabolic precursor, 5'-dAMP is sequentially phosphorylated by intracellular nucleotide kinases to generate deoxyadenosine triphosphate required for genomic DNA replication and cellular repair processes, while demonstrating selective photosensitized degradation specifically under acidic environmental conditions.

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 66 mg/mL (199.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.