CAS No. 84-60-6

Batch: Purity:99.88
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2,6-Dihydroxyanthraquinone Chemical Structure
Chemical Structure
Check the 2,6-Dihydroxyanthraquinone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2,6-dihydroxyanthracene-9,10-dione
CAS Number 84-60-6
Molecular Formula

C14H8O4
Molecular Weight (MW) 240.21
SMILES C1=CC2=C(C=C1O)C(=O)C3=C(C2=O)C=C(C=C3)O
InChIKey APAJFZPFBHMFQR-UHFFFAOYSA-N

Ordering Information

Biological Activity

2,6-Dihydroxyanthraquinone (Anthraflavic acid) is an anthraquinone derivative that acts as a potent and selective inhibitor of cytochrome P-448 activity. By inhibiting cytochrome P-448, this compound modulates xenobiotic metabolism and suppresses the bioactivation of environmental procarcinogens. Consequently, it attenuates downstream mutagenic pathways and cellular transformation phenotypes, serving as a valuable chemical tool for investigating cytochrome P450-mediated metabolic processes and toxicology. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 48 mg/mL (199.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.