CAS No. 146504-07-6

Batch: Purity:98
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(1R,2R)-trans-N-Boc-1,2-cyclohexanediamine Chemical Structure
Chemical Structure
Check the (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 146504-07-6
Molecular Formula

C11H22N2O2
Molecular Weight (MW) 214.30
SMILES CC(C)(C)OC(=O)NC1CCCCC1N

Ordering Information

Biological Activity

(1R,2R)-trans-N-Boc-1,2-cyclohexanediamine is a monoprotected chiral diamine building block and synthetic intermediate. It is widely utilized in organic synthesis and medicinal chemistry as a chiral scaffold for constructing bioactive peptidomimetics, organocatalysts, and small-molecule precursors. Through regioselective functionalization of the unblocked primary amine, this derivative enables the preparation of diverse stereodefined compounds for downstream chemical and biological evaluation.

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 42 mg/mL (195.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.