CAS No. 768-93-4
Batch:
Purity:98
Chemical Structure
Check the
1-Iodoadamantane
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 768-93-4 | |
|---|---|---|
| Molecular Formula |
C10H15I |
|
| Molecular Weight (MW) | 262.13 | |
| SMILES | C1C2CC3CC1CC(C2)(C3)I |
1-Iodoadamantane is a lipophilic adamantane derivative and chemical building block used in medicinal chemistry to introduce the bulky, lipophilic adamantyl group into functionalized bioactive molecules. The incorporation of the adamantyl moiety into pharmaceutical compounds typically enhances lipophilicity, improves cell membrane permeability, and increases metabolic stability against enzymatic degradation, thereby modulating pharmacological profiles and therapeutic efficacy. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
52 mg/mL
(198.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.