CAS No. 83-33-0

Batch: Purity:98
1-Indanone Chemical Structure
Chemical Structure
Check the 1-Indanone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 83-33-0
Molecular Formula

C9H8O

Molecular Weight (MW) 132.16
SMILES C1CC(=O)C2=CC=CC=C21

Ordering Information

Biological Activity

1-Indanone is a cyclic aromatic ketone that functions as a substrate and metabolic intermediate in xenobiotic detoxification, steroid hormone biosynthesis, and arachidonic acid metabolism pathways. It is processed by carbonyl reductases and aldo-keto reductases, undergoing NADPH-dependent reduction to form 1-indanol. This enzymatic conversion modulates cellular redox state, ketone clearance, and downstream lipid signaling pathways involved in cellular metabolism and biochemical processes. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 26 mg/mL (196.73 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.