CAS No. 1476-39-7

Batch: Purity:98.24
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1,5-Diaminopentane dihydrochloride Chemical Structure
Chemical Structure
Check the 1,5-Diaminopentane dihydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1476-39-7
Molecular Formula

C5H16Cl2N2
Molecular Weight (MW) 175.1
SMILES C(CCN)CCN.Cl.Cl

Biological Activity

1,5-Diaminopentane dihydrochloride (Cadaverine dihydrochloride) is a naturally occurring biogenic polyamine formed via the decarboxylation of L-lysine. As a key metabolic intermediate and polyamine analog, it modulates bacterial stress responses, porin channel permeability, and cellular proliferation. Additionally, cadaverine regulates bacterial virulence gene expression and functions as a specific ligand for trace amine-associated receptors to elicit olfactory and neurological signaling pathways. [1][2]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 5 mg/mL (28.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Samartzidou H, et al. J Bacteriol. 1999;181(3):791-8.

[2] Proc. Natl. Acad. Sci. U.S.A. 2012;109(52).

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Note: Technical data last updated: Sep 1, 2026.