CAS No. 331830-20-7
Chemical Structure
Check the
1,4-DPCA
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-oxo-1H-1,10-phenanthroline-3-carboxylic acid | |
|---|---|---|
| CAS Number | 331830-20-7 | |
| Molecular Formula |
C13H8N2O3 |
|
| Molecular Weight (MW) | 240.21 | |
| InChIKey | XZZHOJONZJQARN-UHFFFAOYSA-N |
1,4-DPCA is a competitive inhibitor of prolyl 4-hydroxylase and factor inhibiting HIF (FIH). By inhibiting these hydroxylase enzymes, 1,4-DPCA prevents the degradation of hypoxia-inducible factor-1α (HIF-1α) and attenuates collagen hydroxylation, thereby promoting HIF-1α-mediated gene expression, regulating cellular hypoxic signaling pathways, and modulating extracellular matrix synthesis in fibroblast and connective tissue models.
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Note: Technical data last updated: Sep 1, 2026.