CAS No. 19870-46-3

Batch: Purity:99.47
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1,3-Dicaffeoylquinic acid Chemical Structure
Chemical Structure
Check the 1,3-Dicaffeoylquinic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 19870-46-3
Molecular Formula

C25H24O12
Molecular Weight (MW) 516.45

Biological Activity

1,3-Dicaffeoylquinic acid (cynarin) is a naturally occurring phenolic compound found in artichoke with antioxidant, choleretic, and immunosuppressive properties. It functions as a potent scavenger of reactive oxygen species, protecting hepatocytes and other cells from hydroperoxide-induced oxidative stress and lipid peroxidation. Additionally, 1,3-dicaffeoylquinic acid exhibits antiviral activity through the inhibition of HIV-1 integrase, thereby suppressing viral integration and replication in host cells. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (193.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Gebhardt R. Toxicol Appl Pharmacol. 1997;144(2):279-86.

[2] Robinson WE Jr, et al. Mol Pharmacol. 1996;50(4):846-55.

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Note: Technical data last updated: Sep 1, 2026.