CAS No. 1072-91-9

Batch: Purity:99.91
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1,3,5-Trimethylpyrazole Chemical Structure
Chemical Structure
Check the 1,3,5-Trimethylpyrazole product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1072-91-9
Molecular Formula

C6H10N2
Molecular Weight (MW) 110.16
SMILES CC1=CC(=NN1C)C

Biological Activity

1,3,5-Trimethylpyrazole is a methylated pyrazole derivative that functions as a key heterocyclic building block and intermediate in organic synthesis and medicinal chemistry. Pyrazole-containing structures are widely incorporated into pharmacologically active molecules to target diverse signaling pathways, including kinase signaling and inflammatory cascades. Modification of the pyrazole core enables the development of functionalized derivatives with targeted biological activities across various cellular processes. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (907.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Karrouchi K, et al. Molecules. 2018;23(1).

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Note: Technical data last updated: Sep 1, 2026.