CAS No. 62284-79-1
-p-Bromotetramisole-oxalate-chemical-structure-s7383.gif)
| IUPAC Name | 6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;oxalic acid | |
|---|---|---|
| CAS Number | 62284-79-1 | |
| Molecular Formula |
C13H13BrN2O4S |
|
| Molecular Weight (MW) | 373.22 | |
| SMILES | C1CSC2=NC(CN21)C3=CC=C(C=C3)Br.C(=O)(C(=O)O)O | |
| InChIKey | ZULBIBHDIQCNIS-UHFFFAOYSA-N |
(-)-p-Bromotetramisole Oxalate is a potent, non-specific inhibitor of alkaline phosphatase. By suppressing alkaline phosphatase enzymatic activity, this compound effectively regulates intracellular and extracellular phosphate metabolism. Disruption of alkaline phosphatase signaling alters local phosphate levels, leading to suppressed extracellular matrix mineralization, impaired osteogenic differentiation, and reduced vascular calcification phenotypes across cell-based biological assays.
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
74 mg/mL
(198.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
74 mg/mL
(198.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 74 mg/mL |
| Ethanol | Insoluble |
| DMSO |
75 mg/mL
(200.95 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 75 mg/mL |
| Ethanol | Insoluble |
| Water | 75 mg/mL |
| DMSO |
5 mg/mL
(13.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
| DMSO |
75 mg/mL
(200.95 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 38 mg/mL |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
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- (-)-p-Bromotetramisole Oxalate Solubility in DMSO
- (-)-p-Bromotetramisole Oxalate Stock Solution
- (-)-p-Bromotetramisole Oxalate Storage
- (-)-p-Bromotetramisole Oxalate Stability
- (-)-p-Bromotetramisole Oxalate Molecular Weight
- (-)-p-Bromotetramisole Oxalate SMILES
- (-)-p-Bromotetramisole Oxalate Chemical Structure (2D and 3D)
- (-)-p-Bromotetramisole Oxalate SDS｜MSDS