CAS No. 869988-94-3(free base)
Batch:
Purity:99.90
Chemical Structure
Check the
TLQP-21 TFA
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 869988-94-3(free base) | |
|---|---|---|
| Molecular Formula |
C107H170N40O26(TFA) |
|
| Molecular Weight (MW) | 2546.75 | |
| SMILES | N/A |
TLQP-21 TFA is a VGF-derived neuropeptide that acts as a potent agonist of complement component 3a receptor 1 (C3aR1). Upon receptor engagement, TLQP-21 induces C3aR1 activation via a folding-upon-binding mechanism, triggering intracellular calcium mobilization and downstream intracellular signaling cascades. This peptide plays key functional roles in regulating lipolysis, energy expenditure, microglial activation, and pain pathways. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(39.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(39.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.