CAS No. 14636-12-5
Batch:
Purity:98.45
Chemical Structure
Check the
Terlipressin Acetate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-1-[(4R,7S,10S,13S,16S,19R)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide | |
|---|---|---|
| CAS Number | 14636-12-5 | |
| Molecular Formula |
C52H74N16O15S2 |
|
| Molecular Weight (MW) | 1227.37 | |
| InChIKey | BENFXAYNYRLAIU-QSVFAHTRSA-N |
Terlipressin Acetate is a synthetic vasopressin analogue that acts as a selective vasopressin V1 receptor agonist. Upon cleavage, it releases active lysine vasopressin, which stimulates V1 receptors on vascular smooth muscle cells to trigger intracellular calcium mobilization and smooth muscle contraction. This cascade increases systemic vascular resistance, elevates arterial blood pressure, and restores hemodynamic stability in hypotensive conditions.
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 100 mg/mL |
| Water | 100 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.