CAS No. 39698-78-7
Batch:
Purity:99.10
Chemical Structure
Check the
Saralasin Acetate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 39698-78-7 | |
|---|---|---|
| Molecular Formula |
C44H71N13O13 |
|
| Molecular Weight (MW) | 990.11 | |
| SMILES | O.CNCC(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)C)C(=O)NC(CC1=CC=C(O)C=C1)C(=O)NC(C(C)C)C(=O)NC(CC2=CN=C[NH]2)C(=O)N3CCCC3C(=O)NC(C)C(O)=O.CC(O)=O |
Saralasin Acetate is an octapeptide analog of angiotensin II that acts as a competitive inhibitor of angiotensin II receptors. By blocking angiotensin II binding, it blunts angiotensin-mediated vasoconstriction, aldosterone release, and downstream signaling pathways involved in blood pressure regulation. Consequently, saralasin acetate attenuates pressor responses in vivo and serves as a functional probe for investigating renin-angiotensin system signaling and hypertensive pathophysiology.
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(100.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.