CAS No. 9009-65-8
Chemical Structure
Check the
Protamine sulfate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 9009-65-8 | |
|---|---|---|
| Molecular Formula |
Protamine sulfate is a highly positively charged polycationic protein derived from salmon sperm that functions as a heparin antagonist. It binds electrostatically to negatively charged unfractionated heparin, forming an inactive salt complex lacking anticoagulant activity. This neutralizing interaction prevents heparin-mediated activation of antithrombin, thereby reversing systemic anticoagulation and restoring normal blood coagulation mechanisms. [1]
Note: Technical data last updated: Sep 1, 2026.