CAS No. 86555-35-3
Batch:
Purity:99.27
Chemical Structure
Check the
Malantide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 86555-35-3 | |
|---|---|---|
| Molecular Formula |
C72H124N22O21 |
|
| Molecular Weight (MW) | 1633.89 | |
| SMILES | CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)C(CCC(O)=O)NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(NC(=O)C(CO)NC(=O)CNC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(N)CCCNC(N)=N)C(C)O)C(C)C)C(O)=O |
Malantide is a synthetic dodecapeptide that acts as a highly specific substrate for cAMP-dependent protein kinase (PKA) with a Km of. Derived from the phosphorylation site on the beta-subunit of phosphorylase kinase, it functions as a phosphate acceptor in kinase activity assays. Phosphorylation by PKA regulates phosphorylase kinase activation, downstream glycogen metabolism, and cAMP-dependent signaling cascades. [1]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(61.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.