CAS No. 1450806-98-0

GLP-1 (7-37) Acetate Chemical Structure
Chemical Structure
Check the GLP-1 (7-37) Acetate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (4S)-5-[[2-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[2-[[(2S)-5-carbamimidamido-1-(carboxymethylamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-4-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-4-yl)propanoyl]amino]propanoyl]amino]-5-oxopentanoic acid
CAS Number 1450806-98-0
Molecular Formula

C151H228N40O47
Molecular Weight (MW) 3355.74
InChIKey GCYXWQUSHADNBF-AAEALURTSA-N

Biological Activity

GLP-1 (7-37) Acetate is an endogenous peptide agonist of the glucagon-like peptide-1 receptor (GLP-1R). Derived from proglucagon processing in intestinal L cells, this bioactive peptide stimulates GLP-1R signaling to increase intracellular cyclic AMP production. Activation of downstream cAMP/PKA pathways enhances glucose-dependent insulin secretion, promotes insulin gene expression, and regulates glucose homeostasis in pancreatic islet cells. [1][2]

Solubility

Reference

[1] Mojsov S, et al. J Clin Invest. 1987;79(2):616-9.

[2] Drucker DJ, et al. Proc Natl Acad Sci U S A. 1987;84(10):3434-8.

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Note: Technical data last updated: Sep 1, 2026.