CAS No. 914454-01-6

Batch: Purity:99.92
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Exenatide Acetate (Exendin-4) Chemical Structure
Chemical Structure
Check the Exenatide Acetate (Exendin-4) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 914454-01-6
Molecular Formula

C186H286N50O62S
Molecular Weight (MW) 4246.62

Ordering Information

Biological Activity

Exenatide Acetate (Exendin-4) is a 39-amino acid peptide that functions as a potent glucagon-like peptide-1 receptor (GLP-1R) agonist. Binding to GLP-1R stimulates intracellular cAMP accumulation and activates downstream PKA and EPAC signaling cascades. This activation enhances glucose-dependent insulin secretion, inhibits glucagon release, and promotes pancreatic beta-cell proliferation and survival. [1]

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.