Cagrilintide CAS Number

Cagrilintide is a long-acting acylated amylin analogue that acts as a nonselective agonist at amylin receptors (AMYR) and calcitonin receptors (CTR). Activation of these neuroendocrine receptors engages central neuronal signaling pathways to promote satiety, slow gastric emptying, and significantly decrease food intake. Consequently, these downstream physiological effects suppress body weight gain and modulate metabolic homeostasis in preclinical models of obesity. ^[1]

[1] Kruse T, et al. J Med Chem. 2021;64(15):11183-11194.