CAS No. 128270-60-0

Batch: Purity:99.89
Check CoA
Bivalirudin Trifluoroacetate Chemical Structure
Chemical Structure
Check the Bivalirudin Trifluoroacetate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 128270-60-0
Molecular Formula

C98H138N24O33
Molecular Weight (MW) 2180.33
SMILES CCC(C)C(C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CC(=O)N)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)C4CCCN4C(=O)C(CCCNC(=N)N)NC(=O)C5CCCN5C(=O)C(CC6=CC=CC=C6)N

Ordering Information

Biological Activity

Bivalirudin Trifluoroacetate is a synthetic 20-residue peptide that acts as a specific, reversible direct thrombin inhibitor. By binding simultaneously to both the catalytic site and the anion-binding exosite 1 of thrombin, it blocks thrombin-mediated cleavage of fibrinogen into fibrin. This inhibition prevents fibrin clot formation and suppresses thrombin-induced platelet activation and downstream coagulation cascade signaling.

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.