CAS No. 183552-38-7

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Chemical Information

CAS Number 183552-38-7
Molecular Formula

C72H95ClN14O14

Molecular Weight (MW) 1416.06

Biological Activity

Abarelix is a synthetic peptide and potent gonadotropin-releasing hormone (GnRH) receptor antagonist. It competitively binds to pituitary GnRH receptors, thereby disrupting endogenous GnRH-mediated signal transduction. This targeted receptor inhibition rapidly decreases the secretion of luteinizing hormone and follicle-stimulating hormone, suppressing downstream testosterone biosynthesis without triggering an initial surge in gonadotropin or androgen levels.

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Note: Technical data last updated: Sep 1, 2026.