Clinical Trials

Oxytocin has been evaluated in numerous clinical trials investigating a broad range of neurodevelopmental, psychiatric, and obstetric indications. Clinical studies spanning Early Phase 1 through Phase 4—sponsored primarily by academic medical centers and university hospitals such as Massachusetts General Hospital and University Hospital, Tours—have evaluated the peptide for conditions including autism spectrum disorder, cervical ripening, postpartum hemorrhage, and marijuana dependence. Recruitment across these investigations encompasses completed trials, actively recruiting protocols, as well as terminated or withdrawn studies. Specific protocols include a completed Phase 3 study (NCT02985749) examining social functioning in autism spectrum disorder and an active Phase 3 trial (NCT04949633) evaluating labor induction in patients with an unfavorable cervix.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06039878 ACTIVE_NOT_RECRUITING
Obesity, Childhood; Obesity
University of Michigan
 2023-12-21
NCT05079841 ACTIVE_NOT_RECRUITING
Oxytocin; Labor Pain; Induction of Labor Affected Fetus / Newborn; Physiologic Effects of Drugs
Yale University
 2021-11-15 PHASE4
NCT06194851 RECRUITING
Post-Traumatic Stress Disorder (PTSD)
VA Office of Research and Development
 2024-10-28 PHASE2
NCT07730294 NOT_YET_RECRUITING
Pain; Pituitary Surgery
Yale University
 2026-08 PHASE2
NCT07688512 NOT_YET_RECRUITING
Postpartum Hemorrhage; Uterine Atony; Uterine Atony With Hemorrhage; Elective Cesarean Section
Stony Brook University
 2026-08 PHASE4
NCT07636421 NOT_YET_RECRUITING
Postpartum Hemorrhage; Uterine Atony; Cesarean Section; Blood Loss, Surgical
Mansoura University
 2026-08 PHASE4
NCT06483659 RECRUITING
Postoperative Pain
Brigham and Women's Hospital
 2025-06-01 PHASE2
NCT07366359 RECRUITING
Premature Rupture of Fetal Membranes; Labor, Induced; Cervical Ripening
National Hospital of Obstetrics and Gynecology
 2026-02-10
NCT07430228 ENROLLING_BY_INVITATION
Total Hip Arthroplasty
Wake Forest University Health Sciences
 2026-09 PHASE2
NCT04949633 RECRUITING
Cervical Ripening; Unfavorable Cervix
University Hospital, Tours
 2021-09-28 PHASE3
NCT06710964 NOT_YET_RECRUITING
Mechanistic Self-Dehumanization Condition; Control Condition
Florida State University
 2026-10
NCT06713473 NOT_YET_RECRUITING
Rehumanization Intervention; Control Intervention
Florida State University
 2026-08
NCT02225600 SUSPENDED
Borderline Personality Disorder
Icahn School of Medicine at Mount Sinai
 2014-08-26
NCT07409753 RECRUITING
Acute Pain
Wake Forest University Health Sciences
 2025-10-22 PHASE2
NCT04303702 RECRUITING
Labor Complication
Washington University School of Medicine
 2022-07-01
NCT06990217 NOT_YET_RECRUITING
Induction of Labor; Augmentation of Labor
HaEmek Medical Center, Israel
 2025-06 PHASE4
NCT04789148 RECRUITING
Vasopressin Deficiency
Elizabeth Austen Lawson
 2025-09-10 PHASE1
NCT06364228 RECRUITING
Stress
University of Nebraska
 2026-06-20 PHASE2
NCT07784478 NOT_YET_RECRUITING
Cesarean Section; Hypotension; Postpartum Hemorrhage; Spinal Anesthesia
Khyber Girls Medical College
 2026-09-01
NCT07568509 RECRUITING
Arginine Vasopressin Deficiency; Oxytocin Deficiency; Pediatric Disease; Hypopituitarism
Massachusetts General Hospital
 2026-08-17 EARLY_PHASE1
NCT06676774 RECRUITING
Arginine Vasopressin Deficiency; Diabetes Insipidus
University Hospital, Basel, Switzerland
 2025-05-16 PHASE2
NCT04435704 WITHDRAWN
Osteoarthritis, Knee
Wake Forest University Health Sciences
 2025-01 PHASE2
NCT06334172 RECRUITING
Glucose Metabolism Disorders (Including Diabetes Mellitus)
University Hospital, Gentofte, Copenhagen
 2024-01-01
NCT05664516 RECRUITING
Binge-eating Disorder
Massachusetts General Hospital
 2023-03-07 PHASE2
NCT04218409 RECRUITING
Pain
University of Florida
 2021-09-02 EARLY_PHASE1
NCT03860233 RECRUITING
Sleep Apnea; Sleep Apnea, Obstructive
Vivek Jain
 2019-03-04 PHASE1
NCT04551482 RECRUITING
Obesity, Adolescent; Oxytocin
Massachusetts General Hospital
 2021-07-28 PHASE2
NCT05488457 RECRUITING
Post Partum Hemorrhage; Cesarean Section Complications; Blood Loss
Stanford University
 2025-01-01 PHASE2
NCT06789705 RECRUITING
Central Diabetes Insipidus
University Hospital, Basel, Switzerland
 2025-01-27
NCT05290129 RECRUITING
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2022-08-17
NCT06808516 RECRUITING
Arginine Vasopressin Deficiency; Central Diabetes Insipidus; Oxytocin Deficiency
University Hospital, Basel, Switzerland
 2025-07-01 PHASE2
NCT06285409 RECRUITING
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2024-04-04
NCT05864508 NOT_YET_RECRUITING
Autism Spectrum Disorder
University Hospital, Toulouse
 2023-07 PHASE2
NCT07265180 RECRUITING
Schizophrenia Spectrum Disorders (SSD)
Charite University, Berlin, Germany
 2025-09-08
NCT06987786 NOT_YET_RECRUITING
Spine; Low Back Pain; Neck Pain
Duke University
 2026-06-01
NCT07188207 NOT_YET_RECRUITING
Postpartum Hemorrhage
Assiut University
 2025-10-01
NCT06036004 RECRUITING
Central Diabetes Insipidus (cDI)
University Hospital, Basel, Switzerland
 2024-01-08 PHASE2
NCT07559656 RECRUITING
Healthy
University of Electronic Science and Technology of China
 2026-04-26
NCT07119398 RECRUITING
Preterm PROM (Pregnancy)
Eastern Virginia Medical School
 2025-07-14 PHASE4
NCT05432089 UNKNOWN
Severe Mental Illness
Shalvata Mental Health Center
 2023-03-30 PHASE2
NCT07551882 RECRUITING
Self-compassion Training (SCT) Plus Intranasal Oxytocin; Self-compassion Training (SCT) Plus Intranasal Placebo
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
 2024-01-10 PHASE2
NCT06930391 RECRUITING
Postpartum Hemorrhage (Primary)
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2025-09-15
NCT06469203 UNKNOWN
Missed Abortion
Assuta Ashdod Hospital
 2024-09-01
NCT07609693 RECRUITING
Lactation Disorders
Tokat Gaziosmanpasa University
 2026-05-12
NCT07425938 RECRUITING
Healthy Adult Male
University of Electronic Science and Technology of China
 2026-01-24
NCT04523922 COMPLETED
PTSD; Alcohol Use Disorder
Medical University of South Carolina
 2021-03-29 PHASE2
NCT06372522 NOT_YET_RECRUITING
Pregnancy Related
Rambam Health Care Campus
 2024-04
NCT04903002 ACTIVE_NOT_RECRUITING
Chronic Pain
Memorial University of Newfoundland
 2022-04-01 PHASE2; PHASE3
NCT06460948 COMPLETED
Arginine Vasopressin Deficiency; Oxytocin Deficiency
Elizabeth Austen Lawson
 2024-11-13 EARLY_PHASE1
NCT06268431 RECRUITING
Prolonged Labor; Failed Induction; Labor Dystocia
Christiana Care Health Services
 2024-03-19
NCT04493229 WITHDRAWN
Osteoarthritis, Knee
Wake Forest University Health Sciences
 2024-01 PHASE2
NCT06757517 RECRUITING
Benzodiazepine Dependence
St. Olavs Hospital
 2022-03-01 PHASE2
NCT03232918 RECRUITING
Fetal Bradycardia Complicating Labor and Delivery; Fetal Bradycardia During Labor; Fetal Heart Rate or Rhythm Abnormality Affecting Fetus
Unyime Ituk
 2019-02-20 PHASE4
NCT06403982 UNKNOWN
Uterine Contraction; Oxytocin; Labor Progress; Fetal Doppler; Labor Epidural Analgesia; Labor Pain
Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
 2024-05-06
NCT07140237 RECRUITING
Healthy Adult Male
University of Electronic Science and Technology of China
 2025-09 EARLY_PHASE1
NCT06010368 NOT_YET_RECRUITING
Cesarean Section Complications; Tranexamic Acid; Oxytocin; Post Partum Hemorrhage
Cairo University
 2024-10-01 PHASE3
NCT06960850 NOT_YET_RECRUITING
Propranolol; Labour Induction
Federal Teaching Hospital Abakaliki
 2025-06-01
NCT04433741 WITHDRAWN
Pain, Chronic
Wake Forest University Health Sciences
 2025-01 PHASE2
NCT07093060 RECRUITING
Healhty
University of Electronic Science and Technology of China
 2025-06-09 EARLY_PHASE1
NCT06651476 COMPLETED
Sunburn
Wake Forest University Health Sciences
 2024-12-05 PHASE2
NCT06181396 RECRUITING
Delivery Complication; Cesarean Delivery Affecting Fetus
Rambam Health Care Campus
 2023-10-01
NCT03899597 UNKNOWN
Neonatal Respiratory Distress
Institute for the Care of Mother and Child, Prague, Czech Republic
 2024-01-30
NCT06547437 NOT_YET_RECRUITING
Induced; Birth; Labor Onset and Length Abnormalities
Western Galilee Hospital-Nahariya
 2024-09
NCT06881459 COMPLETED
Type 1 Diabetes
University Hospital, Gentofte, Copenhagen
 2025-03-25
NCT06560099 UNKNOWN
Post Partum Hemorrhage
Ain Shams University
 2024-08-25
NCT06199076 TERMINATED
Alcohol Use Disorder
Karolinska Institutet
 2023-10-17 PHASE2
NCT07053930 COMPLETED
Labor
RESnTEC, Institute of Research
 2024-10-01
NCT05405257 TERMINATED
Hypermobile Ehlers-Danlos Syndrome; Pain Assessment
Baylor College of Medicine
 2022-05-13 PHASE1; PHASE2
NCT06792357 NOT_YET_RECRUITING
36-40 haftalık Hamile
Cukurova University
 2025-01-25
NCT05745935 UNKNOWN
Wound Heal; Scar; Previous Cesarean Section
Egymedicalpedia
 2023-03-01
NCT04228289 COMPLETED
PTSD
VA Office of Research and Development
 2021-01-01 PHASE2
NCT05568745 UNKNOWN
Induction of Labor; Cervical Ripening; Premature Rupture of Fetal Membranes; Nulliparous
University Hospital, Clermont-Ferrand
 2023-01-18 PHASE4
NCT04478942 COMPLETED
Premature Rupture of Membrane; Induction of Labor Affected Fetus / Newborn
University of Wisconsin, Madison
 2020-10-26 EARLY_PHASE1
NCT04431193 WITHDRAWN
Osteoarthritis, Knee
Wake Forest University Health Sciences
 2023-12 PHASE2
NCT03693885 UNKNOWN
Respiratory Insufficiency Syndrome of Newborn; Breastfeeding Status
University of Zurich
 2019-01-01
NCT06248710 RECRUITING
Depressive Symptoms; Human-Animal Interaction
Dr. Karin Hediger
 2024-01-29 PHASE2; PHASE3
NCT06493968 UNKNOWN
Placenta Accreta Spectrum
Cairo University
 2024-07-01
NCT06224127 UNKNOWN
Anxiety Disorders; Alcohol Use Disorder; Stress, Psychological
Soovu Labs Inc.
 2024-07-15 PHASE1
NCT03878589 COMPLETED
Knee Osteoarthritis; Osteoarthritis
University of Florida
 2019-08-06 PHASE2; PHASE3
NCT06325501 UNKNOWN
Myoma;Uterus
Cairo University
 2024-03-01 PHASE3
NCT05511415 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2022-11-02
NCT06189001 COMPLETED
Adiposity
University Hospital, Gentofte, Copenhagen
 2024-01-01
NCT03245437 COMPLETED
Schizophrenia
University of California, Los Angeles
 2018-01-04 PHASE4
NCT06405737 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2024-01-07
NCT05608070 WITHDRAWN
Pain, Postoperative; Analgesia; Postoperative Pain; Pain, Post Operative; Oxytocin
Beth Israel Deaconess Medical Center
 2023-06-01 PHASE4
NCT06889155 COMPLETED
Intraoperative Blood Loss
Cairo University
 2023-08-30
NCT04307069 UNKNOWN
Fetal Infection; Chorioamnionitis; Endometritis; Cesarean Section Complications
Rambam Health Care Campus
 2020-05-01
NCT05865288 UNKNOWN
Eating Disorders
Shalvata Mental Health Center
 2023-06-30 PHASE1
NCT04897802 COMPLETED
Hypopituitarism; Central Diabetes Insipidus; Panhypopituitarism; Psychological Disorder; Social Isolation; Hypothalamic Diseases; Pituitary Diseases; Oxytocin Deficiency
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
 2021-09-13 PHASE4
NCT03865615 WITHDRAWN
Alcohol Use Disorder
Jennifer Mitchell
 2023-11-01 PHASE2
NCT05892939 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2023-05-23
NCT05896553 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2023-05-29
NCT05412524 UNKNOWN
Premature Infant Disease; Development, Infant
University of Virginia
 2022-09-23
NCT05760807 COMPLETED
Methamphetamine Use Disorder
Turning Point
 2023-03-29
NCT05307133 COMPLETED
Obesity, Morbid
Centre Hospitalier Universitaire de Nice
 2022-11-24
NCT03863288 TERMINATED
Irritable Mood
University of Nebraska
 2022-02-18 PHASE1; PHASE2
NCT05037617 COMPLETED
Induced; Birth
University of Calgary
 2021-10-25
NCT03900754 TERMINATED
Schizophrenia
VA Office of Research and Development
 2020-01-13 PHASE2
NCT03846505 COMPLETED
Alcohol Use Disorder; Couples
Medical University of South Carolina
 2019-05-16 PHASE2
NCT05823441 COMPLETED
Oxytocin; Pain; Empathy; Social Familiarity; Analgesia
Peking University People's Hospital
 2023-06-03 PHASE4
NCT04429880 WITHDRAWN
Osteoarthritis, Knee
Wake Forest University Health Sciences
 2023-01 PHASE2
NCT03819231 TERMINATED
Smoking; Smoking Cessation
University of Southern California
 2018-10-10 PHASE2; PHASE3
NCT02762669 TERMINATED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2016-08-03
NCT04051619 COMPLETED
Opioid Use Disorder
Brown University
 2020-01-06 PHASE1
NCT05312008 TERMINATED
Alcohol Use Disorder
Indiana University
 2022-01-16 PHASE2
NCT05672667 COMPLETED
Healthy Volunteer Study
Wake Forest University Health Sciences
 2023-02-27 PHASE1
NCT05077540 UNKNOWN
Labor Complication
Aswan University Hospital
 2021-11-01
NCT05806307 UNKNOWN
Misoprostol Allergy; Oxytocin Allergy; Tranexamic Acid Allergy; Ethamsylate Allergy; Myoma; Blood Loss, Surgical
Cairo University
 2023-03-15 PHASE4
NCT05532215 UNKNOWN
Post Partum Hemorrhage
OZORI EBIOGBO STANLEY
 2023-03-14
NCT05679908 COMPLETED
Chronic Migraine; Chronic Migraine, Headache; Chronic Migraine Without Aura; Aura Migraine
Tonix Pharmaceuticals, Inc.
 2022-12-06 PHASE2
NCT05920707 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2023-04-20
NCT04732247 COMPLETED
Oxidative Stress; Inflammation
Florida Institute for Human and Machine Cognition
 2022-02-01 PHASE2
NCT06325839 COMPLETED
Pregnancy Related
Giresun University
 2023-04-01
NCT05319301 COMPLETED
Oxytocin Deficiency; Hypopituitarism; Hypothalamic Obesity; Pituitary Dysfunction; Central Diabetes Insipidus; Social Isolation
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
 2022-04-01
NCT05207774 UNKNOWN
Obesity; Diabetes; Bariatric Surgery
Soroka University Medical Center
 2020-01-09
NCT06242886 COMPLETED
Breastfeeding, Exclusive; Breastfeeding
Halic University
 2023-02-20
NCT05326776 COMPLETED
Healthy Adults
University of California, San Diego
 2023-04-05 PHASE2
NCT05627791 TERMINATED
Vaginal Atrophy; Oxytocin Gel; Postmenopausal Women; Vaginal Maturation Index
Department of Medical Services Ministry of Public Health of Thailand
 2022-11-30 PHASE2; PHASE3
NCT05899517 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2022-06-22
NCT05341076 UNKNOWN
Dystocia
Assiut University
 2022-08-01
NCT03260920 UNKNOWN
Frontotemporal Dementia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
 2018-01-31 PHASE2
NCT04007224 COMPLETED
Autistic Spectrum Disorder
Fundatia Bio-Forum
 2019-01-17 PHASE1
NCT05110482 UNKNOWN
Adverse Effect of Oxytocic Drugs
Cairo University
 2021-11-30 PHASE4
NCT04906278 COMPLETED
Abortion, Missed
Assiut University
 2021-11-01
NCT06179147 COMPLETED
Postpartum Hemorrhage
Ege University
 2022-11-01
NCT02505984 COMPLETED
Depression, Postpartum; Anxiety
Massachusetts General Hospital
 2016-01 PHASE2
NCT04902235 COMPLETED
Hypopituitarism; Central Diabetes Insipidus; Panhypopituitarism; Psychological Disorder; Social Isolation; Hypothalamic Diseases; Pituitary Diseases; Oxytocin Deficiency
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
 2021-07-06 PHASE4
NCT05664659 COMPLETED
Blood Loss, Surgical; Intrapartum Hemorrhage
Ain Shams Maternity Hospital
 2022-12-20 PHASE4
NCT02872467 COMPLETED
Substance Abuse Problem; Pregnancy
University of North Carolina, Chapel Hill
 2016-05 PHASE1
NCT05467462 COMPLETED
Postpartum Hemorrhage
Bezmialem Vakif University
 2022-08-01
NCT05479357 UNKNOWN
Atonic Postpartum Hemorrhage; High Risk Pregnancy
Sohag University
 2022-07-28
NCT04890470 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2021-03-02
NCT04902729 COMPLETED
Post Partum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2021-07-20
NCT04665440 TERMINATED
Mother-Infant Interaction
University Hospital, Geneva
 2020-09-01
NCT02100956 TERMINATED
Neuropathic Pain
Wake Forest University Health Sciences
 2014-06-19 PHASE2
NCT01996605 TERMINATED
Healthy Volunteer Study
Wake Forest University Health Sciences
 2014-01-02 PHASE2
NCT05207436 COMPLETED
Post Traumatic Stress Disorder; Relational Problems
San Diego Veterans Healthcare System
 2022-01-17 PHASE2
NCT05289869 COMPLETED
Pregnant Patients With Obesity
Ohio State University
 2022-04-06 PHASE4
NCT03636555 WITHDRAWN
Alcohol Use Disorder
University of North Carolina, Chapel Hill
 2019-10 PHASE2
NCT05827731 COMPLETED
Pregnancy Outcomes; Oxytocin; Labor Induction; Mode of Delivery
Changsha Hospital for Maternal and Child Health Care
 2021-09-01
NCT04595812 UNKNOWN
Abdominal Myomectomy; Blood Loss
Cairo University
 2020-11-01 PHASE4
NCT03197662 COMPLETED
Prader-Willi Syndrome; Hyperphagia
Eric Hollander
 2018-04-11 PHASE2
NCT05444738 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2022-04-01
NCT03749902 COMPLETED
Induction of Labor
University of Liverpool
 2020-01-06 PHASE4
NCT04738838 COMPLETED
Cold Exposure
Florida Institute for Human and Machine Cognition
 2022-05-20 PHASE2
NCT04017247 COMPLETED
Induced; Birth
Rambam Health Care Campus
 2019-11-01
NCT06955650 COMPLETED
Pain, Face
Aarhus University Hospital
 2021-04-30 EARLY_PHASE1
NCT04518176 UNKNOWN
Cesarean Section Complications
Aswan University Hospital
 2020-09-01
NCT05382143 UNKNOWN
Endometriosis
Radboud University Medical Center
 2022-02-01 PHASE2
NCT04492072 COMPLETED
Cesarean Section; Misoprostol; Oxytocin; High Risk Pregnancy
Thomas Jefferson University
 2020-08-17
NCT04210310 TERMINATED
Tinnitus
NYU Langone Health
 2020-01-15 PHASE3
NCT05059028 COMPLETED
Oxytocin; Massage; Music; Breastfeeding
Istanbul University - Cerrahpasa
 2021-11-01
NCT02888041 TERMINATED
Cervical Ripening; Pregnancy
University Hospital, Limoges
 2016-12 PHASE3
NCT04648137 COMPLETED
Diabetes Insipidus
University Hospital, Basel, Switzerland
 2021-02-05
NCT04177719 UNKNOWN
Schizophrenia
National Institute of Mental Health and Neuro Sciences, India
 2019-11-08
NCT03852797 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2019-03-28
NCT05215873 COMPLETED
Prelabor Rupture of Membranes
Ain Shams Maternity Hospital
 2021-02-01 PHASE4
NCT03651882 COMPLETED
Postpartum Hemorrhage
University of Zurich
 2018-08-07 PHASE4
NCT04413786 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2019-10-14
NCT04747015 UNKNOWN
Post Partum Hemorrhage
Cairo University
 2020-07-13
NCT04138368 UNKNOWN
Postpartum Depression
HaEmek Medical Center, Israel
 2020-01-01
NCT05073939 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2021-04-01
NCT05247151 COMPLETED
Schizophrenia Spectrum Disorders
Charite University, Berlin, Germany
 2021-08-02
NCT02825641 COMPLETED
Medical Induction of Labor Affecting Newborn
Rambam Health Care Campus
 2016-08-01
NCT04105998 COMPLETED
Chronic Pain Due to Injury
Wake Forest University Health Sciences
 2019-10-24 PHASE4
NCT02121184 TERMINATED
Pregnancy; Labor Pain
Northwestern University
 2014-04
NCT04549012 UNKNOWN
Effect of Drug
Ain Shams University
 2020-09 EARLY_PHASE1
NCT06343480 COMPLETED
Labor Onset and Length Abnormalities
Federal Teaching Hospital Abakaliki
 2020-09-01
NCT04724187 UNKNOWN
Primary; Post Partum Hemorrhage
Islamabad Medical and Dental College
 2021-02-03 PHASE2
NCT03676621 COMPLETED
Postpartum Hemorrhage
Assiut University
 2018-11-01 PHASE4
NCT02824627 COMPLETED
Mood Disorder; Disruptive Behavior Disorders
University of Nebraska
 2017-01-27 PHASE2
NCT04143685 UNKNOWN
Prelabor Rupture of Membranes; Premature Rupture of Membrane
sammour.rami
 2019-12-01
NCT04401839 UNKNOWN
Post Partum Hemorrhage
Cairo University
 2020-05-31
NCT04560218 COMPLETED
To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women
Department of Medical Services Ministry of Public Health of Thailand
 2020-10-30 PHASE3
NCT03904745 UNKNOWN
Infertility, Female
Bezmialem Vakif University
 2020-12-21
NCT03370510 TERMINATED
Autism Spectrum Disorder
Yale University
 2018-12-07 PHASE2
NCT03252496 COMPLETED
Pre-Eclampsia; Cesarean Section
Mansoura University
 2017-08-19
NCT03870503 COMPLETED
Postpartum Hemorrhage
Aswan University Hospital
 2019-04-01
NCT04756089 COMPLETED
Induced; Birth; Labor Long; Labor Pain; Breast Pumping; Lactation Induced
Yale University
 2021-03-13
NCT03211013 COMPLETED
Posttraumatic Stress Disorder
Palo Alto Veterans Institute for Research
 2017-07-10 EARLY_PHASE1
NCT05275270 COMPLETED
Menopause Related Conditions
Al-Azhar University
 2020-12-01
NCT02979093 TERMINATED
Maternal Behavior; Maternal Addiction
Lane Strathearn, MBBS PhD
 2017-05-05 PHASE2
NCT05251610 COMPLETED
Duration of Labor
Darlington-Peter Chibuzor Ugoji
 2020-11-02
NCT03414112 COMPLETED
Anorexia Nervosa
University of Minnesota
 2018-09-25 EARLY_PHASE1
NCT03046836 COMPLETED
Alcohol Use
Medical University of South Carolina
 2017-07-01 PHASE2
NCT04632264 COMPLETED
Postpartum Hemorrhage
Columbia University
 2020-12-10
NCT02849743 COMPLETED
Craniopharyngioma; Hypothalamic Obesity
Shana McCormack, MD
 2016-10 PHASE2
NCT02493426 COMPLETED
Autism Spectrum Disorders
University of Minnesota
 2014-05 PHASE2
NCT03777878 UNKNOWN
Cesarean Section Complications
Aswan University Hospital
 2019-01-01
NCT04707950 UNKNOWN
Postpartum Hemorrhage
Benha University
 2020-01-01 PHASE1; PHASE2
NCT04715737 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2017-12-19
NCT04815395 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2017-12-19
NCT04501809 UNKNOWN
Second Trimester Abortion
Zagazig University
 2020-07-15
NCT03875391 COMPLETED
Intrusive Memories; PTSD
Charite University, Berlin, Germany
 2019-03-06
NCT04493515 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2020-07-28
NCT03168698 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2017-05-25
NCT04320706 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2020-02-20
NCT04386447 WITHDRAWN
Covid-19; Corona Virus Infection; SARS-CoV 2
Azienda Ospedaliero-Universitaria di Parma
 2020-09-01 PHASE2
NCT04656067 COMPLETED
Blood Loss, Surgical; Blood Loss, Postoperative
Egymedicalpedia
 2020-04-01 PHASE1; PHASE2
NCT04137432 UNKNOWN
Loneliness
University Hospital, Bonn
 2019-09-26 PHASE1
NCT03604874 COMPLETED
DELAYED LABOUR
Assiut University
 2018-09-01 PHASE4
NCT02710084 COMPLETED
Phelan-McDermid Syndrome
Alexander Kolevzon
 2016-04-29 PHASE2
NCT02682784 COMPLETED
Cocaine Use Disorder
Medical University of South Carolina
 2015-07 PHASE2
NCT02553226 COMPLETED
Adverse Reaction to Oxytocin
University of Aarhus
 2016-04 PHASE4
NCT02149823 TERMINATED
Borderline Personality Disorder; BPD; Schizotypal Personality Disorder; SPD; Autism Spectrum Disorder; Schizophrenia; Schizoaffective Disorder; Bipolar Disorder
Maria de las Mercedes Perez Rodriguez
 2013-09 PHASE1
NCT03148899 COMPLETED
Sleep Apnea, Obstructive
George Washington University
 2016-07-27 PHASE2
NCT03497988 WITHDRAWN
Obesity
Shana McCormack, MD
 2018-09 PHASE2
NCT02069431 TERMINATED
Inflammation
University of Florida
 2016-02 PHASE1
NCT04306354 UNKNOWN
Cocaine Withdrawal; Cocaine Smoking; Cocaine-Related Disorders
Pontificia Universidade Católica do Rio Grande do Sul
 2018-09-15 PHASE1; PHASE2
NCT03310333 UNKNOWN
PROM (Premature Rupture Of Foetal Membrane)
University Hospital, Clermont-Ferrand
 2018-02-14 PHASE4
NCT03578263 COMPLETED
Cesarean Section Complications
Aswan University Hospital
 2018-04-01
NCT03710304 COMPLETED
Cesarean Section Complications
Aswan University Hospital
 2018-11-01
NCT03361124 WITHDRAWN
Blood Loss Anemia; Uterine Atony With Hemorrhage
Milton S. Hershey Medical Center
 2019-03-01 PHASE4
NCT03929367 COMPLETED
Chronic Pain
Wake Forest University Health Sciences
 2019-05-10 PHASE4
NCT03246919 TERMINATED
Blood Loss, Surgical; Postpartum Hemorrhage; Bleed Pregnancy; Pregnancy Related; Cesarean Section Complications
Loyola University
 2017-09-13 PHASE4
NCT03957083 COMPLETED
Postpartum Hemorrhage; Obesity
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2019-06-26
NCT03892668 COMPLETED
Myomectomy
Cairo University
 2019-04-30 PHASE4
NCT05621694 COMPLETED
Hypertension
Arizona State University
 2017-09-30
NCT04109339 UNKNOWN
Oxytocin; Hemodynamic Monitoring; Laparoscopic Surgery
Yangzhou University
 2019-05-01
NCT03937401 UNKNOWN
Fibroid; Adenomyosis
Turku University Hospital
 2019-02-01 PHASE4
NCT05096676 COMPLETED
Autism Spectrum Disorder; Oxytocin
Prof. Ilanit gordon
 2016-08-01
NCT04328870 COMPLETED
Fluid Overload
University of Jordan
 2018-05-20
NCT03148574 COMPLETED
Post Partum Hemorrhage
Assiut University
 2017-07-02 PHASE3
NCT07436286 COMPLETED
Postpartum Hemorrhage (PPH); Postpartum Hemorrhage Third Stage of Labour Retained Placenta
Dangana Zakari Adeka
 2018-02-01
NCT02567032 COMPLETED
Schizophrenia; Oxytocin; Social Cognition; Psychotic Disorders
University of California, San Francisco
 2010-10 EARLY_PHASE1
NCT02221830 COMPLETED
Preeclampsia
University of Colorado, Denver
 2015-02 EARLY_PHASE1
NCT01869556 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2013-06-04
NCT02742532 COMPLETED
Alcohol Use Disorder; Stress Disorders, Post-Traumatic; Anxiety Disorders; Substance Use Disorders
Jennifer Mitchell
 2017-04-20 PHASE2
NCT06275438 COMPLETED
Healthy Mothers Who Have Had Both Vaginal and Cesarean Deliveries
Kafkas University
 2018-08-25
NCT03293511 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2017-06-09
NCT02595749 COMPLETED
Nicotine Dependence; Tobacco Smoking
University of Southern California
 2016-07 PHASE4
NCT03967171 COMPLETED
Cesarean Section Complications; Postpartum Hemorrhage; Blood Loss, Surgical; Blood Loss, Postoperative; Postoperative Pain; Atony, Uterine
Bezmialem Vakif University
 2019-05-01
NCT03577457 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2018-02-01
NCT03426176 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2018-02-01
NCT03742531 COMPLETED
Oxytocin; Induction of Labor
Zeynep Kamil Maternity and Pediatric Research and Training Hospital
 2018-12-15 PHASE2
NCT02741063 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2016-05 EARLY_PHASE1
NCT04762004 COMPLETED
Preterm Birth; Pain, Procedural
University of Geneva, Switzerland
 2018-03-07
NCT02720978 UNKNOWN
Fetus or Newborn or Maternal; Effects of Induction of Labor
Tel-Aviv Sourasky Medical Center
 2016-05 PHASE3
NCT03339024 COMPLETED
Alcoholism; Substance-Related Disorders
Norwegian University of Science and Technology
 2017-11-01 PHASE3
NCT02999100 TERMINATED
Postpartum Hemorrhage
GlaxoSmithKline
 2016-11-23 PHASE1
NCT03067805 COMPLETED
Sexual Infidelity; Emotional Infidelity; Jealousy
University of Electronic Science and Technology of China
 2016-02
NCT02711189 WITHDRAWN
Alcoholism
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
 2016-03-08 PHASE1
NCT03891095 COMPLETED
Oxytocin Group; L-DOPA Group; Placebo Group
Beijing Normal University
 2018-12-01
NCT02985749 COMPLETED
Autism Spectrum Disorder; Pervasive Developmental Disorder; ASD; PDD
Massachusetts General Hospital
 2017-10-09 PHASE3
NCT03533699 UNKNOWN
Induction of Labor Affected Fetus / Newborn
Ain Shams Maternity Hospital
 2016-10-01
NCT02441673 UNKNOWN
Post Anaesthetic Shivering
Lagos State Health Service Commission
 2018-10-12 PHASE2
NCT02804373 COMPLETED
Prader-Willi Syndrome
University Hospital, Toulouse
 2014-06 PHASE2; PHASE3
NCT03114371 COMPLETED
Prader-Willi Syndrome
University Hospital, Toulouse
 2016-11-28
NCT02775773 COMPLETED
Post Partum Haemorrhage
Azienda U.S.L. 1 di Massa e Carrara
 2018-01-30 PHASE3
NCT02333500 COMPLETED
Anorexia
Fondation Lenval
 2015-02-11
NCT03463993 COMPLETED
Post Partum Hemorrhage
University of Zimbabwe
 2018-04-08 PHASE3
NCT04158167 COMPLETED
Schizophrenia
National Institute of Mental Health and Neuro Sciences, India
 2013-09-01
NCT03128242 UNKNOWN
Healthy
University of Electronic Science and Technology of China
 2016-11-25
NCT03119610 COMPLETED
Obesity; Sarcopenic Obesity; Sarcopenia; Aging; Sedentary Lifestyle
Sara Espinoza
 2017-09-22 PHASE1; PHASE2
NCT02888574 COMPLETED
Chronic Pain; Pelvic Pain
University of Calgary
 2016-11 PHASE2; PHASE3
NCT03225456 UNKNOWN
Weight Gain
Yale-NUS College
 2017-09 PHASE2
NCT03591679 COMPLETED
Post Partum Hemorrhage
Assiut University
 2017-12-01
NCT03001193 COMPLETED
Labor, Obstetric
Dilafor AB
 2016-12 PHASE2
NCT03140488 COMPLETED
Obesity; Labor, Induced; Oxytocin
University of Arizona
 2017-06-05 PHASE4
NCT02216383 COMPLETED
Post Partum Haemorrhage
North Bristol NHS Trust
 2015-02 PHASE3
NCT03085628 UNKNOWN
Mental Health Wellness 1; Social Behavior; Emotion
University of Electronic Science and Technology of China
 2016-07
NCT03486925 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2017-12-19
NCT02881177 COMPLETED
Amphetamine Use Disorders
University of California, San Francisco
 2017-01 PHASE1
NCT02985086 UNKNOWN
Maternal Infection During Pregnancy (Diagnosis); Neonatal Infection
Hospital de Santa Maria, Portugal
 2013-07
NCT02416583 COMPLETED
Failed Induction of Labor
Seoul National University Hospital
 2015-04
NCT03031405 COMPLETED
Intrusive Memories
Charite University, Berlin, Germany
 2017-01-15
NCT03755531 COMPLETED
Postpartum Hemorrhage (Primary)
Al-Kindy College of Medicine
 2018-01-04 PHASE4
NCT03144115 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2016-10 EARLY_PHASE1
NCT03255148 COMPLETED
Oxytocin
KU Leuven
 2017-07-24 PHASE1
NCT03272321 COMPLETED
Oxytocin
KU Leuven
 2017-07-24 PHASE1; PHASE2
NCT03308643 COMPLETED
Myomectomy
Kanuni Sultan Suleyman Training and Research Hospital
 2017-10-01 PHASE4
NCT03081832 COMPLETED
Prader-Willi Syndrome
University Hospital, Toulouse
 2017-01
NCT02302430 COMPLETED
Unit Cohesion
University of California, San Francisco
 2015-10 PHASE1
NCT02847143 COMPLETED
Attachement Style
Centre Hospitalier Universitaire de Besancon
 2015-04-09 PHASE2
NCT02684305 UNKNOWN
Induction of Labor
Tel-Aviv Sourasky Medical Center
 2016-04 PHASE3
NCT03085654 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2017-03-03 EARLY_PHASE1
NCT02090829 WITHDRAWN
Autism Spectrum Disorders
University of Minnesota
 2014-03 PHASE2
NCT03390010 COMPLETED
Cesarean Section
Aljazeera Hospital
 2017-12-28 PHASE1
NCT02469259 COMPLETED
Stress Disorders, Post-Traumatic; Alcoholism
University of California, San Francisco
 2016-02 EARLY_PHASE1
NCT02083809 COMPLETED
Abortion; Dilation and Evacuation; Hemorrhage; Blood Loss
University of Hawaii
 2014-10
NCT03282162 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2017-08-28
NCT02903251 COMPLETED
Alcoholism; Substance-Related Disorders
Norwegian University of Science and Technology
 2016-10 PHASE3
NCT03702946 COMPLETED
Oxytocin and Abdominal Myomectomy
Armed Forces Hospital, Pakistan
 2017-07-15 PHASE3
NCT03245762 COMPLETED
Prader-Willi Syndrome
University of Florida
 2017-08-01 PHASE1; PHASE2
NCT02210598 UNKNOWN
Pregnancy; Labor; Forced or Induced, Affecting Fetus or Newborn
University of Southern California
 2014-03
NCT02983591 COMPLETED
Prevention of Post Partum Hemorrhage After Labor Induction
Makassed General Hospital
 2016-11
NCT01937013 COMPLETED
Frontotemporal Dementia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
 2013-09-12 PHASE2
NCT01573273 COMPLETED
Cocaine Dependence
Medical University of South Carolina
 2012-10
NCT02794779 UNKNOWN
Cesarean Section During Labor
Brasilia University Hospital
 2016-07 PHASE3
NCT01944046 COMPLETED
Autism Spectrum Disorders
Linmarie Sikich
 2014-08-01 PHASE2
NCT01914939 COMPLETED
Autism Spectrum Disorders
Massachusetts General Hospital
 2014-04 PHASE2
NCT02303418 UNKNOWN
Post Partum Haemorrhage
Cairo University
 2014-11 PHASE3
NCT02306733 UNKNOWN
Post Partum Hemorrhage
Cairo University
 2014-11 PHASE3
NCT02302209 COMPLETED
Schizophrenia; Autism Spectrum Disorder
University of California, San Francisco
 2011-04 PHASE1
NCT03074409 COMPLETED
Interoception
University of Electronic Science and Technology of China
 2017-03-02
NCT02801227 UNKNOWN
Premature Rupture of Fetal Membranes
Shaare Zedek Medical Center
 2016-09 PHASE4
NCT02566356 COMPLETED
Schizophrenia; Oxytocin; Social Cognition; Functional Magnetic Resonance Imaging (fMRI)
University of California, San Francisco
 2012-09 EARLY_PHASE1
NCT02969447 COMPLETED
Retained Placenta
University Hospital, Bordeaux
 2016-10-20 PHASE4
NCT01788072 COMPLETED
Autism Spectrum Disorder
Holland Bloorview Kids Rehabilitation Hospital
 2014-06 PHASE2
NCT02410655 WITHDRAWN
Uterine Atony; Postpartum Hemorrhage
NYU Langone Health
 2015-11 PHASE4
NCT03183674 COMPLETED
Autistic Disorder
University of Sao Paulo General Hospital
 2016-07-15 PHASE1
NCT02526914 UNKNOWN
Healthy
David Mankuta
 2015-10
NCT02407340 COMPLETED
Alcoholism; Alcohol Related Disorders
Johns Hopkins University
 2015-03 PHASE1
NCT01865669 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2013-05
NCT03084029 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2016-01 EARLY_PHASE1
NCT02301715 COMPLETED
Emotion; Parent-Child Relations
Centre Hospitalier Universitaire de Besancon
 2014-04-29 PHASE1
NCT06414876 COMPLETED
Animal Assisted Therapy
Uppsala University
 2016-02-02
NCT04505904 COMPLETED
Prolonged Grief Disorder; Bereavement
University of Arizona
 2015-03-20
NCT04629885 COMPLETED
Vulvovaginal Atrophy
PepTonic Medical AB
 2016-05-03 PHASE2
NCT01576874 COMPLETED
Nicotine Dependence
Kevin Gray, MD
 2012-06
NCT03428906 COMPLETED
Healthy
Beijing Normal University
 2016-05-24
NCT01568528 COMPLETED
Schizophrenia
Emory University
 2013-03 PHASE2
NCT02745522 COMPLETED
Oxytocin Effect on Memory Performance During Phase 1; Oxytocin Effect on Memory Performance During Phase 2; Oxytocin Effect on Memory Performance During Phase 3; Oxytocin Effect on Memory Performance During Phase 4
University of Electronic Science and Technology of China
 2015-12 PHASE1
NCT02410759 UNKNOWN
Post Partum Hemorrhage
Cairo University
 2015-04 PHASE3
NCT02911480 WITHDRAWN
Healthy Women of Child Bearing Potential
Oxytone Bioscience BV
 2016-04 PHASE1
NCT03128203 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2016-09
NCT02127073 TERMINATED
Breast Cancer; Ductal Carcinoma in Situ
Montefiore Medical Center
 2015-01-30 PHASE2
NCT02058251 COMPLETED
Alcohol Use Disorders
Medical University of South Carolina
 2014-02 PHASE1
NCT02319707 UNKNOWN
Postpartum Hemorrhage
Yariv yogev
 2015-09 PHASE3
NCT01945957 COMPLETED
Autism Spectrum Disorders
University of North Carolina, Chapel Hill
 2014-09 PHASE1
NCT02723461 UNKNOWN
Failed Induction (of Labor) by Oxytocin
Ain Shams Maternity Hospital
 2016-03 PHASE4
NCT02564068 COMPLETED
Sleep Apnea
George Washington University
 2015-05-22 EARLY_PHASE1
NCT03254628 COMPLETED
Postpartum Hemorrhage; Neonatal Asphyxia
Jhpiego
 2014-11-14
NCT03238924 COMPLETED
PTSD
Medical University of South Carolina
 2015-01-01 PHASE2
NCT03788902 COMPLETED
Attention Deficit Hyperactivity Disorder
Shalvata Mental Health Center
 2014-02-01
NCT02548728 COMPLETED
Opioid Dependence; Opioid Withdrawal
University of North Carolina, Chapel Hill
 2016-02 PHASE1; PHASE2
NCT02568709 COMPLETED
Schizophrenia; Oxytocin; Magnetoencephalography (MEG); Social Cognition
University of California, San Francisco
 2012-02 EARLY_PHASE1
NCT02940574 COMPLETED
Autism Spectrum Disorders
KU Leuven
 2015-04 PHASE4
NCT02091817 SUSPENDED
Healthy; Congenital Prosopagnosia
Soroka University Medical Center
 2013-11 EARLY_PHASE1
NCT02629991 COMPLETED
Prader-Willi Syndrome; Hyperphagia
Montefiore Medical Center
 2015-10 PHASE2
NCT02702674 UNKNOWN
Poor; Labor
Ain Shams Maternity Hospital
 2015-12 PHASE3
NCT03265899 COMPLETED
Healthy Volunteers
University Hospital, Bonn
 2015-07-01 PHASE1
NCT01566539 COMPLETED
Healthy
Emory University
 2008-04
NCT02618499 TERMINATED
Placental Transfusion
Fundacion para la Salud Materno Infantil
 2016-05 PHASE3
NCT02273115 COMPLETED
Labor; Forced or Induced, Affecting Fetus or Newborn
Christiana Care Health Services
 2014-10 PHASE4
NCT02391636 COMPLETED
Postpartum Hemorrhage
Ghamra Military Hospital
 2015-02 PHASE4
NCT01712464 COMPLETED
Impact of Oxytocin on Social Learning
RWTH Aachen University
 2013-10-18
NCT02228031 COMPLETED
Social Cognition; Expressed Emotion
University of Maryland, Baltimore
 2014-10 EARLY_PHASE1
NCT02405715 COMPLETED
Depressive Disorder
Concordia University, Montreal
 2015-02 PHASE2
NCT03010670 COMPLETED
Social Behavior
KU Leuven
 2016-01 PHASE4
NCT02393456 COMPLETED
Social Psychology
University of California, Los Angeles
 2015-01 EARLY_PHASE1
NCT02393443 COMPLETED
Social Psychology
University of California, Los Angeles
 2015-01 EARLY_PHASE1
NCT01712646 TERMINATED
Childhood Onset Psychotic Disorders; Schizophrenia
National Institute of Mental Health (NIMH)
 2012-10-05 PHASE1; PHASE2
NCT01587625 COMPLETED
Birth; Delayed
Göteborg University
 2013-08
NCT01938911 TERMINATED
Essential Hypertension
Insel Gruppe AG, University Hospital Bern
 2014-11
NCT02486822 UNKNOWN
Dystocia
Assiut University
 2015-07
NCT02191423 UNKNOWN
Postpartum Depression
Tel-Aviv Sourasky Medical Center
 2015-01
NCT01780337 COMPLETED
Cardiac Arrhythmia
William Whang
 2013-01 EARLY_PHASE1
NCT01624194 COMPLETED
Autism
Stanford University
 2012-06 PHASE2
NCT02098421 COMPLETED
Induction of Labor
Icahn School of Medicine at Mount Sinai
 2014-11 PHASE1
NCT02963194 COMPLETED
Social Behavior
University of Electronic Science and Technology of China
 2015-11
NCT02602301 UNKNOWN
Neonatal Hyperbilirubinemia
Kasr El Aini Hospital
 2015-11 PHASE4
NCT02861482 COMPLETED
Postpartum Hemorrhage
Dongyu Wang
 2015-01
NCT01931033 COMPLETED
Autism Spectrum Disorders; Pervasive Developmental Disorders; ASD; PDD
Massachusetts General Hospital
 2013-10
NCT02213029 TERMINATED
Embryo Transfer
GlaxoSmithKline
 2014-08-28 PHASE1
NCT02680938 UNKNOWN
Postpartum Hemorrhage
Ain Shams University
 2015-01 PHASE1
NCT02223429 COMPLETED
Healthy
James K. Rilling, PhD
 2014-08
NCT04200599 COMPLETED
Delivery Delayed; Mode of Delivery; Post Partum Hemorrhage; Uterine Hyperstimulation
National University of Malaysia
 2014-08-01
NCT02542813 COMPLETED
Postpartum Hemorrhage
GlaxoSmithKline
 2015-09-14 PHASE1
NCT02238379 COMPLETED
Social Perception
Yale University
 2014-09 EARLY_PHASE1
NCT02063568 WITHDRAWN
Coagulation Changes With Oxytocin
Duke University
 2015-01
NCT02052258 UNKNOWN
Opiate Dependence
MacDonald, Kai, M.D.
 2013-01 PHASE1
NCT02495272 UNKNOWN
Postpartum Bleeding
Bagcilar Training and Research Hospital
 2014-06
NCT02443727 COMPLETED
Healthy
Rodrigo Cardenas
 2015-04 EARLY_PHASE1
NCT01382732 UNKNOWN
Severe Preeclampsia; Postpartum Hemorrhage
Saint Thomas Hospital, Panama
 2012-01 PHASE3
NCT02508220 COMPLETED
Chronic Tinnitus
Berthold Langguth, MD, Ph.D.
 2015-07
NCT02577575 COMPLETED
Schizophrenia; Oxytocin; Social Cognition
University of California, San Francisco
 2010-08 EARLY_PHASE1
NCT02396303 UNKNOWN
Postpartum Haemorrhage
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
 2015-06 EARLY_PHASE1
NCT01908205 COMPLETED
Autism Spectrum Disorder
Holland Bloorview Kids Rehabilitation Hospital
 2013-09 PHASE2
NCT01932060 COMPLETED
Postpartum Hemorrhage
Stanford University
 2013-08 PHASE3
NCT00919802 COMPLETED
Interstitial Cystitis
University of Alabama at Birmingham
 2010-06 PHASE4
NCT01914419 COMPLETED
Postpartum Hemorrhage
Gynuity Health Projects
 2014-04
NCT02740101 COMPLETED
Healthy
University of Electronic Science and Technology of China
 2014-11 EARLY_PHASE1
NCT02013258 COMPLETED
Prader Willi Syndrome
University of Florida
 2015-03 PHASE1
NCT02202083 UNKNOWN
Labor; Forced or Induced, Affecting Fetus or Newborn
West China Second University Hospital
 2014-06 PHASE4
NCT02007447 TERMINATED
Autism Spectrum Disorder
University of Sao Paulo General Hospital
 2015-06 PHASE2; PHASE3
NCT02304042 COMPLETED
Delivery
Cairo University
 2014-11 PHASE3
NCT02501837 COMPLETED
Healthy
University Hospital, Bonn
 2014-07 EARLY_PHASE1
NCT01827332 COMPLETED
Marijuana Dependence
Medical University of South Carolina
 2013-03
NCT02338089 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2015-01
NCT02276677 COMPLETED
Overweight and Obesity
Massachusetts General Hospital
 2014-10 EARLY_PHASE1
NCT01834261 COMPLETED
Brain Dynamics in Healthy Adults
Stony Brook University
 2013-04 PHASE1
NCT01152047 COMPLETED
Dyspepsia; Lack of Satiety
Skane University Hospital
 2010-05
NCT01699997 COMPLETED
Schizophrenia
IRCCS Centro San Giovanni di Dio Fatebenefratelli
 2014-01 PHASE2
NCT02101567 COMPLETED
Bleeding; Anemia
Beni-Suef University
 2014-05 PHASE4
NCT01417026 COMPLETED
Autism Spectrum Disorders
Robert Schultz
 2011-09 PHASE2
NCT01211756 TERMINATED
Major Depressive Disorder; Dysthymia Disorder
David Feifel
 2010-10
NCT01673399 COMPLETED
Implantation Failure
AZ Jan Palfijn Gent
 2012-02 PHASE4
NCT01394471 COMPLETED
Schizophrenia; Schizoaffective Disorder
University of North Carolina, Chapel Hill
 2011-07 PHASE1
NCT02562300 COMPLETED
Postpartum Haemorrhage
Assiut University
 2014-01 PHASE2
NCT02144155 TERMINATED
Schizophrenia
University of California, San Diego
 2012-03
NCT02304055 COMPLETED
Obstetrics
Cairo University
 2013-05 PHASE3
NCT02028533 COMPLETED
Opioid Use Disorder; Cocaine Use Disorder
University of California, San Francisco
 2014-07 PHASE1
NCT01710566 WITHDRAWN
Postpartum Hemorrhage
Gynuity Health Projects
 2013-07 PHASE3
NCT01918475 COMPLETED
Pain; Hyperalgesia; Central Sensitization
Insel Gruppe AG, University Hospital Bern
 2013-07
NCT01728909 COMPLETED
Substance Abuse; Opioid Dependence; Methadone Treatment
University of California, San Francisco
 2012-05 EARLY_PHASE1
NCT02318121 COMPLETED
Prolonged Labor
Assiut University
 2014-04-01 PHASE2
NCT01929161 COMPLETED
Sustained Positive Emotions; Sustained Positive Behavior Change
University of North Carolina, Chapel Hill
 2013-09 PHASE1
NCT01823146 COMPLETED
Aging
University of Florida
 2013-07
NCT01615107 UNKNOWN
Cervix; Insufficient Dilatation in Labor
Hillel Yaffe Medical Center
 2012-07
NCT01012167 COMPLETED
Schizophrenia
University of Maryland, Baltimore
 2010-02 PHASE2
NCT02046499 COMPLETED
Prevention of Post Partum Haemorrhage
University of Pretoria
 2014-01-01
NCT02051231 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2013-12
NCT01829516 COMPLETED
AOD Use, Abuse, and Dependence
University of California, San Francisco
 2013-05 PHASE4
NCT01183221 COMPLETED
Autism; ASD
Alexander Kolevzon
 2010-06-18 PHASE2
NCT00506909 TERMINATED
Schizophrenia
David Feifel
 2008-03
NCT01598623 UNKNOWN
Oxytocin + Non Specific Counselling; Oxytocin + Social Skills Training; Placebo + Non Specific Counselling; Placebo + Social Skills Training
Sheba Medical Center
 2012-05 PHASE2
NCT01975129 COMPLETED
Vaginal Atrophy
PepTonic Medical AB
 2013-09 PHASE2
NCT01513499 COMPLETED
Eating Behavior
Massachusetts General Hospital
 2012-01 EARLY_PHASE1
NCT01711060 COMPLETED
Scarred Uterus
Poitiers University Hospital
 2010-12
NCT01614093 COMPLETED
Schizophrenia
University of Maryland, Baltimore
 2012-06 PHASE4
NCT01719952 COMPLETED
Pregnancy Related; Anaesthesia
Universiti Kebangsaan Malaysia Medical Centre
 2012-01
NCT01386333 COMPLETED
Frontotemporal Dementia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
 2011-06 PHASE1
NCT01397630 TERMINATED
Labour Dystocia
Ottawa Hospital Research Institute
 2012-04 PHASE3
NCT01594775 COMPLETED
Healthy Volunteers
University of Zurich
 2011-10 PHASE1
NCT02229721 COMPLETED
Female Sexual Dysfunction
Medical University of Vienna
 2012-06 PHASE2
NCT02079558 COMPLETED
Postpartum Hemorrhage
Shahid Beheshti University of Medical Sciences
 2012-09 PHASE2
NCT02488642 COMPLETED
Cervical Pregnancy; Maternal Care for Late Fetal Death
National Institute of Perinatology
 2008-05 PHASE4
NCT01722071 COMPLETED
Focus of Study: Neural Correlates of Oxytocin Administration
Tiffany Love
 2012-10 PHASE2
NCT01701180 COMPLETED
Healthy
University Hospital, Bonn
 2012-08 EARLY_PHASE1
NCT02053922 COMPLETED
Postpartum Hemorrhage
Ain Shams University
 2012-12 PHASE3
NCT01108302 WITHDRAWN
Postpartum Hemorrhage
Johns Hopkins Bloomberg School of Public Health
 2011-09
NCT01606462 COMPLETED
Healthy Male Volunteers
University Hospital, Bonn
 2011-06 PHASE1
NCT01600612 UNKNOWN
Postpartum Hemorrhage
Sohag University
 2012-09
NCT01939639 COMPLETED
Healthy Male Volunteers
University Hospital, Bonn
 2013-03 PHASE1
NCT01308749 COMPLETED
Autism
University of North Carolina, Chapel Hill
 2011-03 PHASE2
NCT03335085 COMPLETED
Healthy
Ruhr University of Bochum
 2011-07-01
NCT01256060 COMPLETED
Autism Spectrum Disorder
Evdokia Anagnostou
 2010-11 PHASE2
NCT01849419 COMPLETED
Drug Addiction
University of Chicago
 2010-07
NCT01108289 COMPLETED
Postpartum Hemorrhage
Johns Hopkins Bloomberg School of Public Health
 2011-04
NCT01987804 COMPLETED
Vaginal Atrophy
PepTonic Medical AB
 2012-01 PHASE2
NCT01767025 COMPLETED
Healthy
University Ghent
 2012-11 PHASE3
NCT01551303 COMPLETED
Social Intelligence
Massachusetts General Hospital
 2009-02
NCT01608958 COMPLETED
Postpartum Hemorrhage
Gynuity Health Projects
 2012-05
NCT01963091 COMPLETED
Cocaine Dependence
Medical University of South Carolina
 2011-07 PHASE2
NCT01066299 UNKNOWN
Psychiatric Disorders
University of Zurich
 2010-05
NCT01477840 UNKNOWN
Bleeding Intraoperative
Soudabeh Eshghi ali
 2012-08 PHASE2; PHASE3
NCT01325168 COMPLETED
Post Traumatic Stress Disorder
Rambam Health Care Campus
 2011-08 PHASE4
NCT00787176 TERMINATED
Pregnancy; Labor Pain
Northwestern University
 2007-09
NCT01335789 COMPLETED
Marijuana Dependence
Medical University of South Carolina
 2011-03
NCT01081249 COMPLETED
Behavior; Anxiety
MacDonald, Kai, M.D.
 2008-12 PHASE4
NCT00784797 COMPLETED
Abortion, Missed
Hadassah Medical Organization
 2009-01 PHASE4
NCT01296269 UNKNOWN
Healthy
Hadassah Medical Organization
 2011-04
NCT01011465 COMPLETED
Oxytocin; Placebo
Harvard School of Public Health (HSPH)
 2009-02
NCT01252342 WITHDRAWN
Postpartum Hemorrhage; Uterine Atony
University of Saskatchewan
 2011-08 PHASE4
NCT01689298 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2010-01
NCT01548521 COMPLETED
Prader-Willi Syndrome
University Hospital, Toulouse
 2011-07 PHASE1; PHASE2
NCT00884897 COMPLETED
Social Cognition; Social Anxiety; Emotional Intelligence
University of Maryland, Baltimore
 2010-01 PHASE2
NCT00490802 COMPLETED
Autism
Evdokia Anagnostou
 2006-06 PHASE2
NCT00977769 COMPLETED
Effects of; Anesthesia, in Pregnancy
Oslo University Hospital
 2009-11 PHASE4
NCT01689311 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2009-03
NCT00890630 TERMINATED
Fetal Membranes, Premature Rupture; Induced Labor
McMaster University
 2010-04 PHASE2
NCT01236482 UNKNOWN
Post Partum Hemorrhage
Hadassah Medical Organization
 2010-11 PHASE4
NCT01212185 COMPLETED
Alcohol Withdrawal
University of North Carolina, Chapel Hill
 2010-07 PHASE1
NCT01028677 COMPLETED
Paranoia; Schizophrenia; Schizoaffective Disorder
University of North Carolina, Chapel Hill
 2009-11
NCT01039766 UNKNOWN
Stress Disorders, Post-Traumatic
Sheba Medical Center
 2010-02
NCT01677364 COMPLETED
Heart; Disease,Complicating Pregnancy, Pre-existing
Post Graduate Institute of Medical Education and Research, Chandigarh
 2009-07
NCT00914953 COMPLETED
Social Activity
Claremont Graduate University
 2010-02 EARLY_PHASE1
NCT01002300 COMPLETED
Frontotemporal Dementia; Pick's Disease
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
 2009-09
NCT01099280 COMPLETED
Labor; Induction; PROM (Pregnancy)
Erzincan Military Hospital
 2009-11 PHASE3
NCT01954186 COMPLETED
Postpartum Bleeding
Etlik Zubeyde Hanim Womens' Health and Teaching Hospital
 2010-01
NCT00263796 COMPLETED
Autism
Anagnostou, Evdokia, M.D.
 2006-03 PHASE1
NCT00984347 UNKNOWN
Labor Induction
Hadassah Medical Organization
 2009-11
NCT00963040 COMPLETED
Chronic Daily Headache
MedVadis Research Corporation
 2009-11
NCT00790062 COMPLETED
Uterine Atony; Postpartum Hemorrhage
University of Alabama at Birmingham
 2008-11 PHASE4
NCT01139801 COMPLETED
Induction of Labor
Aultman Health Foundation
 2009-09
NCT01216605 COMPLETED
Health
University Hospital Freiburg
 2009-11 PHASE4
NCT00813436 UNKNOWN
Schizophrenia
Shalvata Mental Health Center
 2008-05 PHASE2
NCT01254045 COMPLETED
Fragile X Syndrome
Stanford University
 2007-02 PHASE2
NCT01038570 COMPLETED
Prader Willi Syndrome
University Hospital, Toulouse
 2009-06 PHASE2
NCT03228901 COMPLETED
Social Interaction
Yale-NUS College
 2007-01 PHASE2
NCT00540748 COMPLETED
Induced Abortion
Asker & Baerum Hospital
 2007-10
NCT01065610 COMPLETED
Coping Skills; Oxytocin; Stress
University of Osnabrueck
 2008-01
NCT00785395 COMPLETED
Uterine Atony
IWK Health Centre
 2008-06 PHASE4
NCT00777166 COMPLETED
Myocardial Ischemia; Hypotension; Bloodloss
Uppsala University
 2005-12 PHASE4
NCT01530230 COMPLETED
Preeclampsia
Uppsala University Hospital
 2005-11
NCT00315913 WITHDRAWN
Dysfunctional Labor
University of California, Irvine
 2004-01 PHASE2
NCT00116350 COMPLETED
Postpartum Hemorrhage
Gynuity Health Projects
 2005-07
NCT00805662 COMPLETED
Idiopathic Infertility
Ludwig-Maximilians - University of Munich
 2003-05
NCT00120042 COMPLETED
Placenta, Retained; Postpartum Hemorrhage
The University of Western Australia
 2005-02
NCT01351402 COMPLETED
Massage; Rest
Claremont Graduate University
 2006-06
NCT00473707 COMPLETED
Postpartum Hemorrhage
Christiana Care Health Services
 2002-08
NCT00504465 COMPLETED
Labor Induction; Cervical Ripening
Weill Medical College of Cornell University
 2002-05
NCT00468520 COMPLETED
Pregnancy; Induced Labor; Cervical Ripening
Columbia University
 2003-11
NCT00405158 COMPLETED
Mastitis
Karlstad University
 2002-01

(data from https://clinicaltrials.gov, updated on 2026-05-15)

Check the Oxytocin (Syntocinon) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Oxytocin selectively binds to the oxytocin G-protein coupled receptor, stimulating phospholipase C activity and cytosolic calcium mobilization to induce uterine smooth muscle contraction and modulate central neurocircuitry governing social behavior. This receptor-mediated signaling mechanism directly supports its clinical evaluation in obstetric procedures such as cervical ripening and postpartum hemorrhage management, as well as therapeutic interventions for autism spectrum disorder and substance dependence.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Jump to

Note: Technical data last updated: Sep 1, 2026.