CAS No. 121062-08-6
Batch:
Purity:99.61
Chemical Structure
Check the
Melanotan II
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide | |
|---|---|---|
| CAS Number | 121062-08-6 | |
| Molecular Formula |
C52H73N15O11 |
|
| Molecular Weight (MW) | 1084.2 | |
| SMILES | CCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)N)NC(=O)C | |
| InChIKey | JDKLPDJLXHXHNV-MFVUMRCOSA-N |
Melanotan II is a synthetic cyclic peptide analog of alpha-melanocyte stimulating hormone (α-MSH) that functions as a potent agonist of melanocortin receptors. By engaging melanocortin receptors such as MC3R and MC4R, it activates downstream melanocortin signaling pathways in the central nervous system, leading to the regulation of energy homeostasis, suppression of food intake, and stimulation of melanogenesis. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 100 mg/mL |
| Water | 100 mg/mL |
| Water | 100 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.