| E6659 |
TYRA-200 |
TYRA-200 is an orally bioavailable inhibitor of FGFR1/2/3 that exhibits potential to address clinically observed acquired resistance alterations in FGFR2, such as molecular brake and gatekeeper mutations. |
| F0647 |
Phospho-FGF Receptor (Tyr653/654) Antibody [F13P7] |
FGFR1 (phospho Y653),Phospho-FGF Receptor (Tyr653/654),Phospho-FGF Receptor 1 (Tyr653/654) |
| E4727 |
TYRA-300 |
TYRA-300 , a 3-pyridylindazole analog, is a reversible and selective inhibitor of FGFR3 with an IC50 of 11 nM in Ba/F3 cells. It also exhibit potent activity in human bladder cancer cell lines harboring FGFR3 activating fusions or mutations. |