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TD52

Cat.No.E8041

TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. This compound mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. It indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. This chemical has less p-EGFR inhibition and has potent anti-cancer activity. It is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
TD52 Chemical Structure

Chemical Structure

Molecular Weight: 360.41

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Chemical Information, Storage & Stability

Molecular Weight 360.41 Formula Storage (From the date of receipt)
CAS No. 1798328-24-1 -- Storage of Stock Solutions Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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