Tianeptine sodium

Catalog No.S1436

Tianeptine sodium is a selective serotonin reuptake enhancer (SSRE) compound used for treating major depressive episodes.

Price Stock Quantity  
In DMSO USD 130 In stock
USD 99 In stock
USD 380 In stock
USD 680 In stock
Bulk Inquiry

Massive Discount Available

Free Overnight Delivery on all orders over $ 500.

Tianeptine sodium Chemical Structure

Tianeptine sodium Chemical Structure
Molecular Weight: 458.93

Validation & Quality Control

Related Compound Libraries

Tianeptine sodium is available in the following compound libraries:

Product Information

  • Compare 5-HT Receptor Modulators
    Compare 5-HT Receptor Modulators
  • Research Area

Product Description

Biological Activity

Tianeptine (INN) (Stablon, Coaxil, Tatinol) is a selective serotonin reuptake enhancer (SSRE) drug used for treating major depressive episodes (mild, moderate, or severe). Unlike conventional tricyclic antidepressants, tianeptine enhances the reuptake of serotonin instead of inhibiting it, opposite to the action of SSRIs. Moreover, it enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D2 and D3 dopamine receptors. There is also action on the NMDA and AMPA receptors. [1]

Chemical Information

Download Tianeptine sodium SDF
Molecular Weight (MW) 458.93
Formula

C21H24ClN2NaO4S

CAS No. 30123-17-2
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Syonnyms Stablon, Coaxil, Tatinol
Solubility (25°C) * In vitro DMSO 92 mg/mL (200 mM)
Water 92 mg/mL (200 mM)
Ethanol 92 mg/mL (200 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name Heptanoic acid, 7-[(3-chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]-, sodium salt (1:1)

Preparing Stock Solutions

Stock Solution (1ml DMSO) 1mM 10mM 20mM 30mM
Mass(mg) 0.45893 4.5893 9.1786 13.7679

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

* Indicates a Required Field

Related 5-HT Receptor Modulators

  • Vortioxetine (Lu AA21004) HBr

    Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. Phase 3.

    Features:A multimodal antidepressant.

  • PRX-08066 Maleic acid

    PRX-08066 is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.

    Features:A selective 5-HT2BR antagonist and high selectivity over the closely related 5-HT2A and 5-HT2C receptors and other receptor targets.

  • (+)-Bicuculline

    (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels.

  • Olanzapine

    Olanzapine is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.

  • Clozapine

    Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.

  • Fluoxetine HCl

    Fluoxetine HCl is an antidepressant of the selective serotonin reuptake inhibitor (SSRI)class.

  • Ketanserin

    Ketanserin is specific 5-HT2A serotonin receptor antagonist with a Ki of 2.5 nM for rat and human 5-HT2A.

  • Agomelatine

    Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.

  • Sumatriptan Succinate

    Sumatriptan Succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.

  • RS-127445

    RS-127445 is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.

Recently Viewed Items

Tags: buy Tianeptine sodium | Tianeptine sodium ic50 | Tianeptine sodium price | Tianeptine sodium cost | Tianeptine sodium solubility dmso | Tianeptine sodium purchase | Tianeptine sodium manufacturer | Tianeptine sodium research buy | Tianeptine sodium order | Tianeptine sodium mouse | Tianeptine sodium chemical structure | Tianeptine sodium mw | Tianeptine sodium molecular weight | Tianeptine sodium datasheet | Tianeptine sodium supplier | Tianeptine sodium in vitro | Tianeptine sodium cell line | Tianeptine sodium concentration | Tianeptine sodium nmr
Contact Us