|
Toll Free: (877) 796-6397 -- USA and Canada only -- |
Fax: +1-832-582-8590 Orders: +1-832-582-8158 |
Tech Support: +1-832-582-8158 Ext:3 Please provide your Order Number in the email. |
Technical Data
| Formula | C27H30O16 |
|||
| Molecular Weight | 610.52 | CAS No. | 153-18-4 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (163.79 mM) | |
| Ethanol | 2 mg/mL (3.27 mM) | |||
| Water | Insoluble | |||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
||||
Preparing Stock Solutions
Biological Activity
| Description | Rutin (Rutoside), a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human. |
|---|---|
| In vitro | Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human. Rutin inhibits platelet aggregation as well as decreases capillary permeability, making the blood thinner and improving circulation. Recent studies show rutin could help prevent blood clots, so could be used to treat patients at risk of heart attacks and strokes. [1] [2] |
| In vivo | LD50: Mice 650mg/kg (i.p.) [3] |
Protocol (from reference)
References
|
Selleck's Rutin has been cited by 8 publications
| Rutin Potentially Binds the Gamma Secretase Catalytic Site, Down Regulates the Notch Signaling Pathway and Reduces Sphere Formation in Colonospheres [ Metabolites, 2022, 12(10)926] | PubMed: 36295828 |
| Rutin increases alpha-tubulin acetylation via histone deacetylase 6 inhibition [ Drug Dev Res, 2022, 10.1002/ddr.21927] | PubMed: 35266183 |
| Genetic and pharmacological PARP inhibition reduces axonal degeneration in C. elegans models of ALS [ Hum Mol Genet, 2022, ddac116] | PubMed: 35594544 |
| The protective effect of rutin against the cisplatin-induced cochlear damage in vitro [ Neurotoxicology, 2022, 90:102-111] | PubMed: 35304134 |
| Prevention of polycystic ovary syndrome and postmenopausal osteoporosis by inhibiting apoptosis with Shenling Baizhu powder compound [ PeerJ, 2022, 10:e13939] | PubMed: 36325179 |
| Role of Flavonoids in the Prevention of AhR-Dependent Resistance During Treatment with BRAF Inhibitors [ Int J Mol Sci, 2020, 21(14):5025] | PubMed: 32708687 |
| Rutin protects boar sperm from cryodamage via enhancing the antioxidative defense. [ Anim Sci J, 2020, 91(1):e13328] | PubMed: 32219925 |
| An antiviral drug screening system for enterovirus 71 based on an improved plaque assay: A potential high-throughput method [ J Med Virol, 2019, 91(8):1440-1447] | PubMed: 30900754 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.