Propidium Iodide

Catalog No.S6874 Batch:S687401

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Technical Data

Formula

C27H34N4.2I

Molecular Weight 668.39 CAS No. 25535-16-4
Solubility (25°C)* In vitro DMSO 100 mg/mL (149.61 mM)
Water 10 mg/mL (14.96 mM)
Ethanol 1 mg/mL (1.49 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Propidium iodide (PI) is a red-fluorescent DNA stain which penetrates only damaged cellular membranes. Propidium iodide (PI) is described for use in the determination of cell viability in cell suspension.

Protocol (from reference)

Selleck's Propidium Iodide has been cited by 11 publications

Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity [ Nat Commun, 2023, 14(1):224] PubMed: 36641456
Nuclear DJ-1 Regulates DNA Damage Repair via the Regulation of PARP1 Activity [ Int J Mol Sci, 2023, 24(10)8651] PubMed: 37239999
Circular RNA circ_0021001 regulates miR-148b-3p/GREM1 axis to modulate proliferation and apoptosis of vascular smooth muscle cells [ Metab Brain Dis, 2022, 37(6):2027-2038] PubMed: 35689751
Circ_0005576 Exerts an Oncogenic Role in Cervical Cancer via miR-1305-Dependent Regulation of PAIP1 [ Reprod Sci, 2022, 10.1007/s43032-022-00925-y] PubMed: 35378711
Pepsin enhances glycolysis to promote malignant transformation of vocal fold leukoplakia epithelial cells with dysplasia [ Eur Arch Otorhinolaryngol, 2022, 10.1007/s00405-022-07729-5] PubMed: 36380093
Circular RNA circVPRBP serves as a microRNA-106b-5p sponge to regulate proliferation and metastasis of cervical cancer cells via tripartite motif-containing protein 3 [ Anticancer Drugs, 2022, 33(9):850-860] PubMed: 35946546
Circular RNA circ-RNF121 contributes to cisplatin (DDP) resistance of non-small-cell lung cancer cells by regulating the miR-646/SOX4 axis [ Anticancer Drugs, 2022, 33(1):e186-e197] PubMed: 34387608
Chamaejasmenin E from Stellera chamaejasme induces apoptosis of hepatocellular carcinoma cells by targeting c-Met in vitro and in vivo [ Bioorg Chem, 2021, S0045-2068(21)00887-7] PubMed: 34844768
Circular RNA circ-MMP11 Contributes to Lapatinib Resistance of Breast Cancer Cells by Regulating the miR-153-3p/ANLN Axis [ Front Oncol, 2021, 11:639961] PubMed: 34295807
Long Non-Coding RNA JPX Contributes to Tumorigenesis by Regulating miR-5195-3p/VEGFA in Non-Small Cell Lung Cancer [ Cancer Manag Res, 2021, 13:1477-1489] PubMed: 33613033

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.