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Technical Data
| Formula | C35H36ClNO3S |
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| Molecular Weight | 586.18 | CAS No. | 158966-92-8 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (170.59 mM) | |
| Ethanol | 10 mg/mL (17.05 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Montelukast(MK0476) is a leukotriene receptor antagonist used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. |
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Protocol (from reference)
Selleck's Montelukast has been cited by 6 publications
| A targeted extracellular vesicles loaded with montelukast in the treatment of demyelinating diseases [ Biochem Biophys Res Commun, 2022, 594:31-37] | PubMed: 35066377 |
| Leukotriene receptor antagonists enhance HCC treatment efficacy by inhibiting ADAMs and suppressing MICA shedding [ Cancer Immunol Immunother, 2021, 70(1):203-213] | PubMed: 32683508 |
| Chronobiological activity of cysteinyl leukotriene receptor 1 during basal and induced autophagy in the ARPE-19 retinal pigment epithelial cell line [ Aging (Albany NY), 2021, 13(24):25670-25693] | PubMed: 34919533 |
| Studium vlivu vybraných inhibitorů proteinkináz na lékovou rezistenci zprostředkovanou cytochromy P450 [ CU Digital Repository, 2021, N/A] | PubMed: None |
| Montelukast, a cysteinyl leukotriene receptor antagonist, inhibits the growth of chronic myeloid leukemia cells through apoptosis. [ Oncol Rep, 2018, 40(2):902-908] | PubMed: 29845257 |
| Modulation of leukotriene signaling inhibiting cell growth in chronic myeloid leukemia. [ Leuk Lymphoma, 2017, 58(8):1903-1913] | PubMed: 27931141 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.