Brassinolide

Catalog No.S3882 Batch:S388202

Technical Data

Formula	C₂₈H₄₈O₆
Molecular Weight	480.68	CAS No.	72962-43-7
Solubility (25°C)*	In vitro	DMSO	96 mg/mL (199.71 mM)
		Ethanol	24 mg/mL (49.92 mM)
		Water	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description	Brassinolide, a plant steroid isolated from Brassica napus pollen, promotes cell elongation and cell devision and thus regulates plant growth and development.
In vitro	Brassinolide is a naturally occurring plant hormone that promotes growth, increases yields for grain and fruit crops, and makes plants more resistant to drought and cold weather. Brassinolide could induce a time and concentration-dependent cytotoxicity in PC-3 cells. Treatment with brassinolide triggers a time-dependent decrease in the expression of anti-apoptotic protein Bcl-2 and marked accumulation in G2/M phase of cell cycle^[1].

Description

Brassinolide, a plant steroid isolated from Brassica napus pollen, promotes cell elongation and cell devision and thus regulates plant growth and development.

In vitro

Brassinolide is a naturally occurring plant hormone that promotes growth, increases yields for grain and fruit crops, and makes plants more resistant to drought and cold weather. Brassinolide could induce a time and concentration-dependent cytotoxicity in PC-3 cells. Treatment with brassinolide triggers a time-dependent decrease in the expression of anti-apoptotic protein Bcl-2 and marked accumulation in G2/M phase of cell cycle^[1].

Protocol (from reference)

Cell Assay:^{^[1]}	Cell lines PC-3 cells Concentrations 0, 10, 20 and 40 μM Incubation Time 12, 24 and 36 h Method PC-3 cells are treated with various concentrations of brassinolide (0, 10, 20 and 40 μM) for 12, 24 and 36 h.

References

[1] Wu YD, et al. Pharmazie. 2007, 62(5):392-5.

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

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