Valpromide

Catalog No.S4991 Batch:S499101

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Technical Data

Formula

C8H17NO

Molecular Weight 143.23 CAS No. 2430-27-5
Solubility (25°C)* In vitro DMSO 28 mg/mL (195.48 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Valpromide (Depamide, Dipropylacetamide, 2-propylpentanamide) is an antiepileptic drug, derivative of Valproic acid (VPA), used as a mood-stabilizer in bipolar disorder. Valpromide inhibits both viral and cellular gene expression. Valpromide is a human epoxide hydrolase inhibitor.

Protocol (from reference)

Selleck's Valpromide has been cited by 5 publications

Valproic acid decreases vascular smooth muscle cell proliferation via protein phosphatase 2A-mediated p70 S6 kinase inhibition [ Biochem Biophys Res Commun, 2022, 606:94-99] PubMed: 35339758
Histone deacetylase inhibitors differentially regulate c-Myc expression in retinoblastoma cells. [ Oncol Lett, 2020, 19(1):460-468] PubMed: 31897159
Inhibition of HDAC4 Attenuated JNK/c-Jun-Dependent Neuronal Apoptosis and Early Brain Injury Following Subarachnoid Hemorrhage by Transcriptionally Suppressing MKK7. [ Front Cell Neurosci, 2019, 13:468] PubMed: 31708743
Establishment and Identification of a CiPSC Lineage Reprogrammed from FSP-tdTomato Mouse Embryonic Fibroblasts (MEFs). [ Stem Cells Int, 2018, 2018:5965727] PubMed: 30675169
CCR7 preservation via histone deacetylase inhibition promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells [ Exp Cell Res, 2018, 371(1):231-237] PubMed: 30107147

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.