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Technical Data
| Formula | C29H50O2 |
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| Molecular Weight | 430.71 | CAS No. | 10191-41-0 | |
| Solubility (25°C)* | In vitro | Ethanol | 100 mg/mL (232.17 mM) | |
| DMSO | 16 mg/mL warmed with 50ºC water bath (37.14 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | (±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage. | |||||
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| Density | 0.950 g/mL at 20 °C | |||||
Protocol (from reference)
Selleck's (±)-α-Tocopherol has been cited by 8 publications
| Targeting N-glycosylation of 4F2hc mediated by glycosyltransferase B3GNT3 sensitizes ferroptosis of pancreatic ductal adenocarcinoma [ Cell Death Differ, 2023, 30(8):1988-2004] | PubMed: 37479744 |
| Silibinin Inhibits Cell Ferroptosis and Ferroptosis-Related Tissue Injuries [ Antioxidants (Basel), 2023, 12(12)2119] | PubMed: 38136238 |
| α-tocopherol pretreatment alleviates cerebral ischemia-reperfusion injury in rats [ CNS Neurosci Ther, 2022, 28(6):964-970] | PubMed: 35301808 |
| Effect of α-tocopherol in alleviating the lipopolysaccharide-induced acute lung injury via inhibiting nuclear factor kappa-B signaling pathways [ Bioengineered, 2022, 13(2):3958-3968] | PubMed: 35112986 |
| HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes [ J Mol Cell Cardiol, 2021, 150:65-76] | PubMed: 33098823 |
| HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes [ J Mol Cell Cardiol, 2021, 150:65-76] | PubMed: 33098823 |
| Tailored theranostic nanoparticles cause efficient ferroptosis in head and neck squamous cell carcinoma through a reactive oxygen species “butterfly effect” [ CHEM ENG J, 2021, 10.1016/j.cej.2021.130083] | PubMed: None |
| Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1. [ Cell Death Dis, 2017, 8(2):e2612] | PubMed: 28182003 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.