Madecassic acid

Catalog No.S9502 Batch:S950201

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Technical Data

Formula

C30H48O6

Molecular Weight 504.70 CAS No. 18449-41-7
Solubility (25°C)* In vitro DMSO 100 mg/mL (198.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Madecassic acid (Brahmic acid), a natural triterpene first isolated from C. asiatica, has diverse anti-inflammatory and anti-diabetic effects, blocking NF-κB activation in macrophages and causing by iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 inhibition.
Targets
IL-1β [1] NF-κB [1] iNOS [1] COX-2 [1] TNF-α [1]

Protocol (from reference)

Selleck's Madecassic acid has been cited by 1 publication

Madecassic Acid Ameliorates the Progression of Osteoarthritis: An in vitro and in vivo Study [ Drug Des Devel Ther, 2022, 16:3793-3804] PubMed: 36345305

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.