Indometacin Sodium

Catalog No.S5010 Batch:S501001

Print

Technical Data

Formula

C19H21ClNNaO7

Molecular Weight 433.82 CAS No. 74252-25-8
Solubility (25°C)* In vitro DMSO 87 mg/mL (200.54 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Indometacin Sodium (Indomethacin Sodium) is the sodium salt of indomethacin, which is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2 with anti-inflammatory, analgesic-antipyretic and tocolytic effects.
Targets
COX1 [1] COX2 [1]
0.11 μM 0.78 μM

Protocol (from reference)

Selleck's Indometacin Sodium has been cited by 3 publications

Arachidonic acid drives adaptive responses to chemotherapy-induced stress in malignant mesothelioma [ J Exp Clin Cancer Res, 2021, 40(1):344] PubMed: 34727953
Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation [ Mol Cell, 2020, 80(3):525-540.e9] PubMed: 33068521
Cross-resistance Among Next Generation Anti-Androgen Drugs Through the AKR1C3/AR-V7 Axis in Advanced Prostate Cancer [ Mol Cancer Ther, 2020, 19;molcanther00152020] PubMed: 32430485

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.