Chlortetracycline HCl (NSC 13252)

Catalog No.S4156 Batch:S415605

Technical Data

Formula	C₂₂H₂₃ClN₂O₈.HCl
Molecular Weight	515.34	CAS No.	64-72-2
Solubility (25°C)*	In vitro	4-Methylpyridine	5 mg/mL warmed with 50ºC water bath (9.7 mM)
		DMSO	Insoluble
		Water	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description	Chlortetracycline HCl (NSC 13252, 7-Chlorotetracycline, Aureomycin monohydrochloride) is the first identified tetracycline antibiotic.
In vitro	Chlortetracycline HCl obtained from Streptomyces aureofaciens, is a broad-spectrum antibacterial agent with activity against a wide range of Gram-positive and Gram-negative bacteria, including obligate anaerobes. Chlortetracycline HCl binds strongly to a single site on the 30S subunit. Chlortetracycline HCl inhibits bacterial growth primarily by inhibiting protein synthesis at the level of the ribosome. ^[1] Chlortetracycline HCl is activity against Streptococcus pyogelles, Diplococcus pneuliloniap, Bacillus subtilis, Streptococcus faecalis, Bacillus subtilis, Mycobacterium ranae with MIC of 0.292, 0.098, 0.195, 0.3, 0.15, 0.3 mg/L. ^[2]

Description

Chlortetracycline HCl (NSC 13252, 7-Chlorotetracycline, Aureomycin monohydrochloride) is the first identified tetracycline antibiotic.

In vitro

Chlortetracycline HCl obtained from Streptomyces aureofaciens, is a broad-spectrum antibacterial agent with activity against a wide range of Gram-positive and Gram-negative bacteria, including obligate anaerobes. Chlortetracycline HCl binds strongly to a single site on the 30S subunit. Chlortetracycline HCl inhibits bacterial growth primarily by inhibiting protein synthesis at the level of the ribosome. ^[1] Chlortetracycline HCl is activity against Streptococcus pyogelles, Diplococcus pneuliloniap, Bacillus subtilis, Streptococcus faecalis, Bacillus subtilis, Mycobacterium ranae with MIC of 0.292, 0.098, 0.195, 0.3, 0.15, 0.3 mg/L. ^[2]

Protocol (from reference)

References

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

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