BCH

Catalog No.S6894 Batch:S689402

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Technical Data

Formula

C8H13NO2

Molecular Weight 155.19 CAS No. 20448-79-7
Solubility (25°C)* In vitro Water 31 mg/mL (199.75 mM)
DMSO Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description BCH (2-Aminobicyclo-(2,2,1)-heptane-2-carboxylic acid, LAT1-IN-1) is a selective and competitive inhibitor of system L amino acid transporter 1 (LAT1). BCH (LAT1-IN-1) induces apoptosis in cancer cells.
Targets
LAT1 [1]

Protocol (from reference)

Selleck's BCH has been cited by 5 publications

Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes [ J Immunother Cancer, 2023, 11(6)e006728] PubMed: 37344101
Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes [ J Immunother Cancer, 2023, 11(6)e006728] PubMed: 37344101
Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment [ Cell Death Dis, 2023, 14(8):525] PubMed: 37582769
Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment [ Cell Death Dis, 2023, 14(8):525] PubMed: 37582769
MAPK signaling regulates c-MYC for melanoma cell adaptation to asparagine restriction [ EMBO Rep, 2021, e51436] PubMed: 33554439

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.