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Technical Data
| Formula | C14H16N2 |
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| Molecular Weight | 212.29 | CAS No. | 104054-27-5 | |
| Solubility (25°C)* | In vitro | DMSO | 42 mg/mL (197.84 mM) | |
| Ethanol | 42 mg/mL (197.84 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Atipamezole (MPV-1248, MPV1248, Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. | |
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Protocol (from reference)
| Animal Study:[1] |
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Selleck's Atipamezole has been cited by 3 publications
| Dexmedetomidine promotes the progression of hepatocellular carcinoma through hepatic stellate cell activation [ Exp Mol Med, 2020, 10.1038/s12276-020-0461-6] | PubMed: 32632241 |
| Dexmedetomidine protects against lipopolysaccharide-induced early acute kidney injury by inhibiting the iNOS/NO signaling pathway in rats. [ Nitric Oxide, 2019, 85:1-9] | PubMed: 30659917 |
| Upregulation of GLT-1 via PI3K/Akt Pathway Contributes to Neuroprotection Induced by Dexmedetomidine. [ Front Neurol, 2019, 10:1041] | PubMed: 31611842 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.