Alcaftadine

Catalog No.S4625 Batch:S462501

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Technical Data

Formula

C19H21N3O

Molecular Weight 307.39 CAS No. 147084-10-4
Solubility (25°C)* In vitro Ethanol 61 mg/mL (198.44 mM)
DMSO 28 mg/mL (91.08 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Alcaftadine (Lastacaft, R89674) is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.
Targets
H1 receptor [1]
(Cell-free assay)
H2 receptor [1]
(Cell-free assay)
H4 receptor [1]
(Cell-free assay)
8.5(pKi) 7.2(pKi) 5.8(pKi)

Protocol (from reference)

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.