Taxifolin (Dihydroquercetin)

Catalog No.S2366 Batch:S236604

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Technical Data

Formula

C15H12O7

Molecular Weight 304.25 CAS No. 480-18-2
Solubility (25°C)* In vitro DMSO 60 mg/mL (197.2 mM)
Ethanol 60 mg/mL (197.2 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
Targets
VEGFR2 kinase [4]
In vitro Taxifolin is not mutagenic and low toxic compared to Qercetin. [1] It acts as a potential chemopreventive agent by regulating genes via an ARE-dependent mechanism. [2] Taxifolin has shown to inhibit the ovarian cancer cell growth in a dose-dependent manner. [3]

Protocol (from reference)

Selleck's Taxifolin (Dihydroquercetin) has been cited by 3 publications

Development of a genetic framework to improve the efficiency of bioactive delivery from blueberry [ Sci Rep, 2020, 10(1):17311] PubMed: 33057109
An antiviral drug screening system for enterovirus 71 based on an improved plaque assay: A potential high-throughput method [ J Med Virol, 2019, 91(8):1440-1447] PubMed: 30900754
Cell-based assay system for high-throughput screening of anti-photo-aging agents in fibroblast transfectants. [Lee S, et al. Cytotechnology, 2016, 68(4):1633-40] PubMed: 26281901

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.